Document Detail

Hyperviscosity syndrome in rheumatoid arthritis with Felty's syndrome: case report and review of the literature.
MedLine Citation:
PMID:  11954894     Owner:  NLM     Status:  MEDLINE    
Hyperviscosity syndrome (HVS) is characterised by high serum viscosity and the involvement of multiple organs, commonly causing retinal haemorrhage, bleeding diathesis, pulmonary hypertension, congestive heart failure (CHF), neurologic deficits and death. It has been reported that HVS is mostly encountered in Waldenström's macroglobulinaemia (80%-90% of all HVS cases) and occasionally in multiple myeloma. HVS in patients with connective tissue diseases (CTD) has rarely been reported. Of 28 cases of HVS reported in patients with CTD, 19 were with seropositive rheumatoid arthritis (RA). However, only six of these 19 cases had Felty's syndrome. Here we report another case of HVS in a patient with RA as well as Felty's syndrome.
S I Zakzook; M B Yunus; D S Mulconrey
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Clinical rheumatology     Volume:  21     ISSN:  0770-3198     ISO Abbreviation:  Clin. Rheumatol.     Publication Date:  2002 Feb 
Date Detail:
Created Date:  2002-04-16     Completed Date:  2002-10-08     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8211469     Medline TA:  Clin Rheumatol     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  82-5     Citation Subset:  IM    
University of Illinois College of Medicine at Peoria, 61656, USA.
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MeSH Terms
Arthritis, Rheumatoid / blood*,  complications*
Blood Viscosity*
Felty's Syndrome / complications*

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