Document Detail

Hyperventilation in tricyclic antidepressant poisoning.
MedLine Citation:
PMID:  509968     Owner:  NLM     Status:  MEDLINE    
A patient with severe tricyclic antidepressant poisoning who showed recurrent ventricular fibrillation and wide QRS complexes on the ECG, failed to respond to intravenous physostigmine and lidocaine. Deliberate artificial hyperventilation was immediately effective in preventing further arrhythmia and in decreasing the width of the QRS complexes. Hyperventilation, a neglected treatment, may be immediately effective in the treatment of severe tricyclic antidepressant poisoning.
M E Kingston
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Critical care medicine     Volume:  7     ISSN:  0090-3493     ISO Abbreviation:  Crit. Care Med.     Publication Date:  1979 Dec 
Date Detail:
Created Date:  1980-02-15     Completed Date:  1980-02-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0355501     Medline TA:  Crit Care Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  550-1     Citation Subset:  AIM; IM    
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MeSH Terms
Amitriptyline / poisoning*
Antidepressive Agents, Tricyclic / poisoning*
Lidocaine / therapeutic use
Physostigmine / therapeutic use
Respiration, Artificial*
Ventricular Fibrillation / chemically induced*,  drug therapy,  therapy
Reg. No./Substance:
0/Antidepressive Agents, Tricyclic; 137-58-6/Lidocaine; 50-48-6/Amitriptyline; 57-47-6/Physostigmine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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