Document Detail


Hyperventilation during exercise in very low birth weight school-age children may implicate inspiratory muscle weakness.
MedLine Citation:
PMID:  22050873     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: To study the ventilatory response during exercise in 8- to 10-year-old children born in 1998 to 2000 with a birthweight <1500 g (very low birthweight [VLBW]).
STUDY DESIGN: We studied 19 VLBW children and 20 full-term children paired for age and sex. A physical activity questionnaire was administered. Lean body mass, spirometry, and maximal inspiratory pressure were assessed at rest. Gas exchange, breathing pattern, and the tension-time index of the inspiratory muscles, a noninvasive indicator of inspiratory muscle effort, were evaluated during a continuous incremental cycling protocol.
RESULTS: VLBW children had lower weight, height, lean body mass, and maximal inspiratory pressure than control subjects. Their physical activity level was not different. During exercise, they had a higher respiratory rate and minute ventilation for the same metabolic level (VCO(2)/kg) and a higher tension-time index of the inspiratory muscles for the same exercise level (percentage of maximal oxygen consumption).
CONCLUSIONS: The lower inspiratory muscle strength observed in school-age VLBW children resulted in a higher inspiratory effort during incremental exercise. The rapid but not shallow breathing pattern adopted by this population during exercise may have been in response to their lower inspiratory muscle resistance to fatigue. VLBW children complaining of dyspnea should be investigated with exercise testing.
Authors:
Aline Rideau Batista Novais; Stephan Matecki; Audrey Jaussent; Marie-Christine Picot; Pascal Amedro; Sophie Guillaumont; Jean-Charles Picaud; Gilles Cambonie
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2011-11-01
Journal Detail:
Title:  The Journal of pediatrics     Volume:  160     ISSN:  1097-6833     ISO Abbreviation:  J. Pediatr.     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-02-14     Completed Date:  2012-03-27     Revised Date:  2012-07-18    
Medline Journal Info:
Nlm Unique ID:  0375410     Medline TA:  J Pediatr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  415-420.e1     Citation Subset:  AIM; IM    
Copyright Information:
Copyright © 2012 Mosby, Inc. All rights reserved.
Affiliation:
Neonatal Intensive Care Unit, Arnaud de Villeneuve Hospital, University Hospital of Montpellier, F-34000 France.
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MeSH Terms
Descriptor/Qualifier:
Anthropometry
Bronchopulmonary Dysplasia / therapy
Child
Exercise / physiology*
Humans
Hyperventilation / physiopathology*
Infant, Newborn
Infant, Very Low Birth Weight*
Muscle Weakness / physiopathology*
Oxygen Consumption
Premature Birth*
Respiration, Artificial
Respiratory Function Tests
Respiratory Muscles / physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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