| Hypervascular thyroid nodules on time-resolved MR angiography at 3 T: radiologic-pathologic correlation. | |
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MedLine Citation:
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PMID: 18356417 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: Detection of a thyroid nodule, either incidental or as a result of related symptomatology, is an extremely common event, often inducing considerable uncertainty regarding the requirement for and best means of further investigation. Whereas tissue sampling represents the sole means of true characterization of these lesions, a number of imaging characteristics have been suggested as potential indicators of the presence of malignancy. The potential value of time-resolved MR angiography, whereby a minimal dose of i.v. contrast agent is dynamically depicted during the first pass of the bolus through the various compartments of circulation, has recently been realized, particularly so with regard to supraaortic angiography. However, it is not uncommon during such temporal imaging to identify focal hyperenhancing thyroid nodules, the significance of which has not previously been described in the literature. We describe the frequency of occurrence and potential significance of this finding, using pathologic correlation where available. CONCLUSION: The prevalence of malignancy in incidentally detected focal hyperenhancing thyroid parenchymal nodules during time-resolved MR angiography is significant, representing 8.3% (1/12) of patients for whom cytologic correlation was available. Further investigation is certainly warranted when encountering such a lesion in clinical practice, particularly because it appears as though time-resolved MR angiography is of no value in the pathologic discrimination of such incidentally identified lesions. |
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Authors:
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Derek G Lohan; Anderanik Tomasian; Roya Saleh; Mayil Krishnam; J Paul Finn |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: AJR. American journal of roentgenology Volume: 190 ISSN: 1546-3141 ISO Abbreviation: AJR Am J Roentgenol Publication Date: 2008 Apr |
Date Detail:
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Created Date: 2008-03-21 Completed Date: 2008-05-06 Revised Date: 2013-05-20 |
Medline Journal Info:
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Nlm Unique ID: 7708173 Medline TA: AJR Am J Roentgenol Country: United States |
Other Details:
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Languages: eng Pagination: W255-60 Citation Subset: AIM; IM |
Affiliation:
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Department of Radiological Sciences, David Geffen School of Medicine at UCLA, Peter V. Ueberroth Bldg., Ste. 3371, 10945 Le Conte Ave., Los Angeles, CA 90095-7206, USA. derek.lohan@gmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Contrast Media / administration & dosage Female Gadolinium DTPA / administration & dosage, diagnostic use Humans Imaging, Three-Dimensional Injections, Intravenous Magnetic Resonance Angiography / methods* Male Middle Aged Neovascularization, Pathologic / diagnosis*, pathology Prevalence Retrospective Studies Thyroid Neoplasms / diagnosis*, epidemiology, pathology Thyroid Nodule / diagnosis*, epidemiology, pathology |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 80529-93-7/Gadolinium DTPA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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