Document Detail

Hyperuricemia and gout: an update.
MedLine Citation:
PMID:  6895439     Owner:  NLM     Status:  MEDLINE    
Gout may be a primary or a secondary disorder. In both types of gout, overproduction or underexcretion of uric acid, or a combination of these abnormalities, may be the underlying mechanism. Controversy exists over the need for treatment of asymptomatic hyperuricemia. Treatment of tophi requires use of both uricosurics and allopurinol. A xanthine oxidase inhibitor is the drug of choice for patients with uric acid stones and for those with renal insufficiency.
A K Khachadurian
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American family physician     Volume:  24     ISSN:  0002-838X     ISO Abbreviation:  Am Fam Physician     Publication Date:  1981 Dec 
Date Detail:
Created Date:  1982-01-28     Completed Date:  1982-01-28     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  1272646     Medline TA:  Am Fam Physician     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  143-8     Citation Subset:  AIM; IM    
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MeSH Terms
Allopurinol / therapeutic use
Gout* / diet therapy,  metabolism,  prevention & control
Kidney / metabolism
Kidney Diseases / blood,  drug therapy,  metabolism
Metabolic Clearance Rate
Middle Aged
Uric Acid / blood*,  metabolism,  urine
Uricosuric Agents / therapeutic use
Xanthine Oxidase / antagonists & inhibitors
Reg. No./Substance:
0/Uricosuric Agents; 315-30-0/Allopurinol; 69-93-2/Uric Acid; EC Oxidase

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