| Hypertrophic obstructive cardiomyopathy, bleeding history, and acquired von Willebrand syndrome: response to septal myectomy. | |
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MedLine Citation:
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PMID: 21364113 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Bleeding with severe aortic stenosis is linked to acquired von Willebrand syndrome and loss of high-molecular-weight multimers of von Willebrand factor. Valve replacement resolves bleeding tendency and loss of high-molecular-weight multimers. We report outcomes in 5 patients with symptomatic obstructive hypertrophic cardiomyopathy and spontaneous gastrointestinal, mucosal, or excessive postsurgical bleeding in whom acquired von Willebrand syndrome was documented. All 5 patients underwent surgical septal myectomy with resolution of acquired von Willebrand syndrome. |
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Authors:
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Joseph L Blackshear; Hartzell V Schaff; Steve R Ommen; Dong Chen; William L Nichols |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Mayo Clinic proceedings. Mayo Clinic Volume: 86 ISSN: 1942-5546 ISO Abbreviation: Mayo Clin. Proc. Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-03-02 Completed Date: 2011-05-31 Revised Date: 2011-09-13 |
Medline Journal Info:
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Nlm Unique ID: 0405543 Medline TA: Mayo Clin Proc Country: United States |
Other Details:
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Languages: eng Pagination: 219-24 Citation Subset: AIM; IM |
Affiliation:
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Division of Cardiovascular Diseases, Mayo Clinic, Jacksonville, FL 32224, USA. blackshear.joseph@mayo.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Cardiomyopathy, Hypertrophic / complications*, surgery* Female Gastrointestinal Hemorrhage / etiology*, therapy Heart Septum / surgery* Humans Male Middle Aged Postoperative Complications Treatment Outcome von Willebrand Diseases / etiology*, surgery* |
| Comments/Corrections | |
Comment In:
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Mayo Clin Proc. 2011 Mar;86(3):181-2
[PMID:
21364110
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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