Document Detail

Hypertrophic chronic pachymeningitis as a localized immune process in the craniocervical region.
MedLine Citation:
PMID:  11148246     Owner:  NLM     Status:  MEDLINE    
Hypertrophic chronic pachymeningitis (HCP) is a rare disorder that causes intracranial or spinal thickening of the dura mater. This report describes a patient with progressive HCP in the craniocervical region associated with signs of rheumatic disease. A ventricular-atrial shunt had to be inserted because of increased intracranial pressure. The patient improved after suboccipital craniotomy, C1 to C6 laminectomy, and removal of the thickened dura. Additional therapy with methotrexate stopped progression, which was documented by MRI and PET.
B Voller; K Vass; J Wanschitz; K Machold; S Asenbaum; M Hoberstorfer; E Auff
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Neurology     Volume:  56     ISSN:  0028-3878     ISO Abbreviation:  Neurology     Publication Date:  2001 Jan 
Date Detail:
Created Date:  2001-01-26     Completed Date:  2001-06-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401060     Medline TA:  Neurology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  107-9     Citation Subset:  AIM; IM    
Department of Neurology, University of Vienna, Austria.
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MeSH Terms
Cerebrospinal Fluid Shunts
Cervical Vertebrae
Chronic Disease
Dura Mater / immunology*,  pathology*
Immunosuppressive Agents / administration & dosage
Magnetic Resonance Imaging
Meningitis / drug therapy,  immunology*,  pathology*
Methotrexate / administration & dosage
Middle Aged
Tomography, Emission-Computed
Reg. No./Substance:
0/Immunosuppressive Agents; 59-05-2/Methotrexate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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