Document Detail


Hypertrophic cardiomyopathy without hypertrophy: two families with myocardial disarray in the absence of increased myocardial mass.
MedLine Citation:
PMID:  2278798     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Two families are described in which individuals showed widespread myocardial disarray at histological examination, in the absence of macroscopic cardiac hypertrophy. In one family the clinical presentation was that of sudden unexpected cardiac death in four family members; members of the other family presented with electrocardiographic repolarisation changes and abnormalities of left ventricular diastolic function. The finding of myocardial disarray, the characteristic histological abnormality of hypertrophic cardiomyopathy, in the absence of increased cardiac mass suggests a wider range of abnormality in hypertrophic cardiomyopathy than is currently recognised.
Authors:
W J McKenna; J T Stewart; P Nihoyannopoulos; F McGinty; M J Davies
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British heart journal     Volume:  63     ISSN:  0007-0769     ISO Abbreviation:  Br Heart J     Publication Date:  1990 May 
Date Detail:
Created Date:  1991-03-11     Completed Date:  1991-03-11     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0370634     Medline TA:  Br Heart J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  287-90     Citation Subset:  AIM; IM    
Affiliation:
Department of Cardiological Sciences, St George's Hospital Medical School, London.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Cardiomyopathy, Hypertrophic / genetics*,  pathology,  physiopathology
Death, Sudden / etiology
Echocardiography
Electrocardiography
Female
Humans
Male
Myocardium / pathology*
Pedigree
Comments/Corrections
Comment In:
Br Heart J. 1990 May;63(5):263-4   [PMID:  2149030 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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