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Hypertrophic cardiomyopathy: Part 1 - Introduction, pathology and pathophysiology.
MedLine Citation:
PMID:  24732610     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiovascular disease with many genotype and phenotype variations. Earlier terminologies, hypertrophic obstructive cardiomyopathy and idiopathic hypertrophic sub-aortic stenosis are no longer used to describe this entity. Patients present with or without left ventricular outflow tract (LVOT) obstruction. Resting or provocative LVOT obstruction occurs in 70% of patients and is the most common cause of heart failure. The pathology and pathophysiology of HCM includes hypertrophy of the left ventricle with or without right ventricular hypertrophy, systolic anterior motion of mitral valve, dynamic and mechanical LVOT obstruction, mitral regurgitation, diastolic dysfunction, myocardial ischemia, and fibrosis. Thorough understanding of pathology and pathophysiology is important for anesthetic and surgical management.
Authors:
Praveen Kerala Varma; Praveen Kumar Neema
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of cardiac anaesthesia     Volume:  17     ISSN:  0974-5181     ISO Abbreviation:  Ann Card Anaesth     Publication Date:    2014 Apr-Jun
Date Detail:
Created Date:  2014-04-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9815987     Medline TA:  Ann Card Anaesth     Country:  India    
Other Details:
Languages:  eng     Pagination:  118-24     Citation Subset:  IM    
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