Document Detail


Hyperthyroidism and myasthenia gravis with features of Eaton-Lambert syndrome.
MedLine Citation:
PMID:  181696     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In a 50-year-old man with hyperthyroidism and myasthenic weakness electrophysiologic phenomena similar to Eaton-Lambert syndrome were seen in classical myasthenia gravis. The orbicularis oculi showed an abnormally small muscle action potential in response to nerve stimulus and unusual facilitation of the response with activity. These signs are compatible with Eaton-Lambert syndrome, but the findings obtained from the adductor pollicis were typical of classical myasthenia. A possible common basis for hyperthyroidism and such an electrophysiologic complexity of transmission failure was considered as a pathogenic hypothesis.
Authors:
M Mori; M Takamori
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Neurology     Volume:  26     ISSN:  0028-3878     ISO Abbreviation:  Neurology     Publication Date:  1976 Sep 
Date Detail:
Created Date:  1976-10-01     Completed Date:  1976-10-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401060     Medline TA:  Neurology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  882-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Evoked Potentials
Facial Nerve / physiopathology
Humans
Hyperthyroidism / complications*,  physiopathology
Male
Middle Aged
Muscles / physiopathology
Muscular Diseases / complications*
Myasthenia Gravis / complications*,  physiopathology
Neural Conduction
Neuromuscular Junction* / physiology
Synaptic Transmission
Syndrome
Ulnar Nerve / physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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