| Hyperthyroidism in pregnancy: diagnosis and treatment. | |
MedLine Citation:
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PMID: 10447008 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Hyperthyroidism due to autoimmune Graves' disease is the leading cause of thyrotoxicosis in pregnant women. The peak incidence of the disease is in the second through the fourth decade of life, which encompasses the reproductive years for women. Although menstrual irregularity is frequent in women with mild to moderate hyperthyroidism, convincing evidence that fertility is impaired is lacking. In general, 2 of every 1000 pregnancies have been reported to be complicated by hyperthyroidism. Hyperthyroidism associated with pregnancy may pose a challenging diagnostic and therapeutic dilemma. The current review focuses on the discussion of symptomatology and diagnosis of the disease, on therapeutic options available to women presenting with hyperthyroidism during gestation, and on the controversy surrounding maternal and fetal outcome in pregnancies complicated by thyrotoxicosis. |
Authors:
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U S Masiukiewicz; G N Burrow |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review |
Journal Detail:
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Title: Thyroid : official journal of the American Thyroid Association Volume: 9 ISSN: 1050-7256 ISO Abbreviation: Thyroid Publication Date: 1999 Jul |
Date Detail:
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Created Date: 1999-09-21 Completed Date: 1999-09-21 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 9104317 Medline TA: Thyroid Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 647-52 Citation Subset: IM |
Affiliation:
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Department of Medicine, Yale University School of Medicine, New Haven, Connecticut 06520-8050, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adrenergic beta-Antagonists
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therapeutic use Antithyroid Agents / therapeutic use Female Graves Disease / complications, diagnosis, therapy Humans Hyperthyroidism / diagnosis*, therapy* Iodine Radioisotopes / therapeutic use Pregnancy Pregnancy Complications / diagnosis*, therapy* Pregnancy Outcome Propylthiouracil / therapeutic use Thyroidectomy Thyrotoxicosis / etiology |
| Grant Support | |
ID/Acronym/Agency:
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KO8 DK02596-01/DK/NIDDK NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic beta-Antagonists; 0/Antithyroid Agents; 0/Iodine Radioisotopes; 51-52-5/Propylthiouracil |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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