Document Detail


Hyperthyroidism and other causes of thyrotoxicosis: management guidelines of the American Thyroid Association and American Association of Clinical Endocrinologists.
MedLine Citation:
PMID:  21510801     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Thyrotoxicosis has multiple etiologies, manifestations, and potential therapies. Appropriate treatment requires an accurate diagnosis and is influenced by coexisting medical conditions and patient preference. This article describes evidence-based clinical guidelines for the management of thyrotoxicosis that would be useful to generalist and subspeciality physicians and others providing care for patients with this condition.
METHODS: The development of these guidelines was commissioned by the American Thyroid Association in association with the American Association of Clinical Endocrinologists. The American Thyroid Association and American Association of Clinical Endocrinologists assembled a task force of expert clinicians who authored this report. The task force examined relevant literature using a systematic PubMed search supplemented with additional published materials. An evidence-based medicine approach that incorporated the knowledge and experience of the panel was used to develop the text and a series of specific recommendations. The strength of the recommendations and the quality of evidence supporting each was rated according to the approach recommended by the Grading of Recommendations, Assessment, Development, and Evaluation Group.
RESULTS: Clinical topics addressed include the initial evaluation and management of thyrotoxicosis; management of Graves' hyperthyroidism using radioactive iodine, antithyroid drugs, or surgery; management of toxic multinodular goiter or toxic adenoma using radioactive iodine or surgery; Graves' disease in children, adolescents, or pregnant patients; subclinical hyperthyroidism; hyperthyroidism in patients with Graves' ophthalmopathy; and management of other miscellaneous causes of thyrotoxicosis.
CONCLUSIONS: One hundred evidence-based recommendations were developed to aid in the care of patients with thyrotoxicosis and to share what the task force believes is current, rational, and optimal medical practice.
Authors:
Rebecca S Bahn Chair; Henry B Burch; David S Cooper; Jeffrey R Garber; M Carol Greenlee; Irwin Klein; Peter Laurberg; I Ross McDougall; Victor M Montori; Scott A Rivkees; Douglas S Ross; Julie Ann Sosa; Marius N Stan; ;
Publication Detail:
Type:  Journal Article; Practice Guideline     Date:  2011-04-21
Journal Detail:
Title:  Thyroid : official journal of the American Thyroid Association     Volume:  21     ISSN:  1557-9077     ISO Abbreviation:  Thyroid     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-06-13     Completed Date:  2011-09-26     Revised Date:  2011-10-28    
Medline Journal Info:
Nlm Unique ID:  9104317     Medline TA:  Thyroid     Country:  United States    
Other Details:
Languages:  eng     Pagination:  593-646     Citation Subset:  IM    
Affiliation:
Division of Endocrinology, Metabolism, and Nutrition, Mayo Clinic , Rochester, Minnesota 55905, USA. bahn.rebecca@mayo.edu
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adrenergic beta-Antagonists / therapeutic use
Antithyroid Agents / therapeutic use
Child
Evidence-Based Medicine
Female
Graves Disease / therapy
Humans
Hyperthyroidism / therapy*
Iodine Radioisotopes / therapeutic use
Pregnancy
Thyroid Crisis / therapy
Thyroid Hormones / therapeutic use
Thyroidectomy
Thyrotoxicosis / diagnosis,  therapy*
Chemical
Reg. No./Substance:
0/Adrenergic beta-Antagonists; 0/Antithyroid Agents; 0/Iodine Radioisotopes; 0/Thyroid Hormones
Comments/Corrections
Comment In:
Thyroid. 2011 Jun;21(6):581-4   [PMID:  21663419 ]
Thyroid. 2011 Jun;21(6):585-91   [PMID:  21663420 ]
Thyroid. 2011 Jun;21(6):573-6   [PMID:  21663417 ]
Thyroid. 2011 Jun;21(6):577-80   [PMID:  21663418 ]
Erratum In:
Thyroid. 2011 Oct;21(10):1169

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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