Document Detail


Hyperthermia in combination with radiation therapy for treatment of advanced inoperable breast cancer.
MedLine Citation:
PMID:  12948269     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Twelve breast cancer patients with locally advanced inoperable lesions were studied. Six cases had received chemotherapy, 6 had not. Most of the tumors were ulcerative lesions with an average size of 11.5 cm. The patients were treated with 43 degrees C hyperthermia once or twice a week together with radiation at a dose of 20-70 Gy. Six of them were also treated with concurrent chemotherapy. Two cases responded completely (17%) and 10 cases responded partially (83%). The result indicates that the combination of hyperthermia and radiation, with or without chemotherapy, might be a good treatment option for locally advanced inoperable breast cancer, especially for patients who have had failure or contraindication to chemotherapy. It is an effective treatment for palliation of local symptoms, showing a tendency to achieve local control of large, ulcerative advanced breast lesions especially when such treatment is followed by salvage surgery.
Authors:
Nantakan Iemwananonthachai; Pittayapoom Pattaranutaporn; Yaowalak Chansilpa; Maturoth Sukkasem
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the Medical Association of Thailand = Chotmaihet thangphaet     Volume:  86     ISSN:  0125-2208     ISO Abbreviation:  J Med Assoc Thai     Publication Date:  2003 Aug 
Date Detail:
Created Date:  2003-09-01     Completed Date:  2004-01-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7507216     Medline TA:  J Med Assoc Thai     Country:  Thailand    
Other Details:
Languages:  eng     Pagination:  715-21     Citation Subset:  IM    
Affiliation:
Radiation Oncology Division, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Breast Neoplasms / radiography,  radiotherapy,  therapy*
Female
Humans
Hyperthermia, Induced*
Middle Aged
Radiotherapy Dosage
Tomography, X-Ray Computed

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