| Hypertensive heart disease: effects of lifestyle modifications and antihypertensive drug treatment. | |
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MedLine Citation:
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PMID: 15225120 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Target-organ protection in hypertensive patients has become increasingly important. This review will focus on hypertensive heart disease that is mainly characterized by myocardial hypertrophy and increased interstitial fibrosis. Cardiac remodeling develops as an adaptive response but actually represents a powerful independent risk factor for cardiovascular morbidity and mortality. The review will begin with a brief discussion on the complex pathophysiology of hypertensive cardiac remodeling and its clinical consequences. The effects of nonpharmacologic and pharmacologic antihypertensive treatments on the development and progression of hypertensive heart disease are presented. Finally, the impact of the regression of myocardial hypertrophy and fibrosis on cardiac function and cardiovascular risk are discussed. |
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Authors:
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Anna Maria Grandi |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Expert review of cardiovascular therapy Volume: 2 ISSN: 1744-8344 ISO Abbreviation: Expert Rev Cardiovasc Ther Publication Date: 2004 Jul |
Date Detail:
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Created Date: 2004-06-30 Completed Date: 2007-10-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101182328 Medline TA: Expert Rev Cardiovasc Ther Country: England |
Other Details:
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Languages: eng Pagination: 617-25 Citation Subset: IM |
Affiliation:
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Department of Clinical Medicine, University of Insubria, Viale Borri 57, 21100, Varese, Italy. amgrandi@libero.it |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antihypertensive Agents
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therapeutic use* Cardiomyopathy, Hypertrophic / etiology, therapy* Endomyocardial Fibrosis / etiology, therapy* Humans Hypertension / complications*, therapy* Life Style* |
| Chemical | |
Reg. No./Substance:
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0/Antihypertensive Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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