| Hypertensive disorders in pregnancy: screening by systolic diastolic and mean arterial pressure at 11-13 weeks. | |
| | |
MedLine Citation:
|
PMID: 20818956 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
OBJECTIVES: To examine the performance of screening for hypertensive disorders in pregnancy and to compare systolic blood pressure (BP), diastolic BP, and mean arterial pressure (MAP) measured by validated automated devices in a large population of pregnant women at 11-13 weeks. METHODS: We recorded maternal variables and measured BP by automated devices in 9149 women with singleton pregnancies. The performance of screening for preeclampsia (PE) and gestational hypertension (GH) by combinations of disease-specific maternal factor-derived a priori risk with systolic BP, diastolic BP, and MAP was determined. RESULTS: There were 8061 cases that were unaffected by PE or GH, 37 that developed PE requiring delivery before 34 weeks (early-PE), 128 with late-PE, and 140 with GH. The systolic BP, diastolic BP, and MAP were significantly higher in early-PE, late-PE, and GH than in the controls (p < 0.0001). The systolic BP was significantly higher in early-PE than in late-PE (p = 0.008) and both systolic BP and MAP were significantly higher in early-PE than in GH (p < 0.01). The best performance in screening was provided by MAP. The detection rate of early-PE at a 10% false-positive rate increased from 47% in screening by maternal factor-derived a priori risk alone to 76% in screening by its combination with MAP. The respective detection rates for late-PE increased from 41 to 52% and for GH increased from 31 to 48%. CONCLUSION: The measurement of BP can be combined with the maternal factor-derived a priori risk to provide effective first-trimester screening for PE and GH. |
| | |
Authors:
|
Leona C Y Poon; Nikos A Kametas; Catalina Valencia; Teodora Chelemen; Kypros H Nicolaides |
Related Documents
:
|
16142596 - Captopril administered at night restores the diurnal blood pressure rhythm in adequatel... 17472026 - Daytime, home and office blood pressures in treated hypertensive patients according to ... 20849356 - Factors affecting the difference between morning and evening home blood pressure: the f... 12691506 - The association of peritoneal transport properties with 24-hour blood pressure levels i... 12218536 - Set positive end-expiratory pressure during protective ventilation affects lung injury. 17094536 - Intracerebral hemorrhage following enucleation: a result of surgery or anesthesia?--a c... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-09-06 |
Journal Detail:
|
Title: Hypertension in pregnancy : official journal of the International Society for the Study of Hypertension in Pregnancy Volume: 30 ISSN: 1525-6065 ISO Abbreviation: Hypertens Pregnancy Publication Date: 2011 |
Date Detail:
|
Created Date: 2011-01-06 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9421297 Medline TA: Hypertens Pregnancy Country: England |
Other Details:
|
Languages: eng Pagination: 93-107 Citation Subset: IM |
Affiliation:
|
Harris Birthright Research Centre for Fetal Medicine, King's College Hospital, London, UK. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Increased myogenic responses of resistance-sized mesenteric arteries after reduced uterine perfusion...
Next Document: Examining the effect of maternal obesity on outcome of labor induction in patients with preeclampsia...