Document Detail

Hypertension and myocardial ischemia.
MedLine Citation:
PMID:  19427499     Owner:  NLM     Status:  MEDLINE    
Detailed studies over the past 30 years have built up an impressive evidence base for the presence of myocardial ischemia in patients who have hypertension. This relationship ranges from the obvious association with obstructive coronary artery disease to mechanisms related to hemodynamic, microcirculatory, and neuroendocrine abnormalities. All of these factors serve to destabilize the critical balance between myocardial oxygen supply and demand. We have at our disposal a range of sophisticated investigations that allow us to demonstrate the presence and extent of the ischemia and therefore to target specific therapies to reduce the risk to these patients. Achieving target BP and managing all reversible components of the patient's cardiovascular risk status reduce to a minimum the clinical sequelae of myocardial ischemia in this vulnerable population..
Brian P Murphy; Tony Stanton; Francis G Dunn
Related Documents :
18997059 - Calcitonin gene-related peptide receptor antagonism does not affect the severity of myo...
19185369 - 2-dimensional strain echocardiography and early detection of myocardial ischemia.
22673889 - Abrogation of lectin-like oxidized ldl receptor-1 attenuates acute myocardial ischemia-...
20431289 - Association of kidney dysfunction with silent lacunar infarcts and white matter hyperin...
24461769 - Meta-analysis of effects of optimization of cardiac resynchronization therapy on left v...
2240629 - No finding of increased myocardial ischemia during or after carotid endarterectomy unde...
9683909 - Evidence for an influence of mechanical restitution on beat-to-beat variations in haemo...
17607039 - Comparison of contrast-enhanced mri with (18)f-fdg pet/201tl spect in dysfunctional myo...
1682069 - Prevention of supraventricular arrhythmias after coronary artery bypass surgery. a meta...
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Medical clinics of North America     Volume:  93     ISSN:  1557-9859     ISO Abbreviation:  Med. Clin. North Am.     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-05-11     Completed Date:  2009-06-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985236R     Medline TA:  Med Clin North Am     Country:  United States    
Other Details:
Languages:  eng     Pagination:  681-95     Citation Subset:  AIM; IM    
Cardiac Department, Stobhill Hospital, Glasgow, Scotland, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Antihypertensive Agents / therapeutic use
Coronary Artery Disease / etiology
Endothelium / physiopathology
Hypertension / complications*,  diagnosis,  drug therapy,  physiopathology
Myocardial Ischemia / diagnosis,  drug therapy,  etiology*,  physiopathology
Myocardium / pathology
Neurosecretory Systems
Oxidative Stress
Risk Factors
Reg. No./Substance:
0/Antihypertensive Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Hypertension and cardiac failure in its various forms.
Next Document:  The kidney, hypertension, and remaining challenges.