| Hypertension and myocardial ischemia. | |
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MedLine Citation:
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PMID: 19427499 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Detailed studies over the past 30 years have built up an impressive evidence base for the presence of myocardial ischemia in patients who have hypertension. This relationship ranges from the obvious association with obstructive coronary artery disease to mechanisms related to hemodynamic, microcirculatory, and neuroendocrine abnormalities. All of these factors serve to destabilize the critical balance between myocardial oxygen supply and demand. We have at our disposal a range of sophisticated investigations that allow us to demonstrate the presence and extent of the ischemia and therefore to target specific therapies to reduce the risk to these patients. Achieving target BP and managing all reversible components of the patient's cardiovascular risk status reduce to a minimum the clinical sequelae of myocardial ischemia in this vulnerable population.. |
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Authors:
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Brian P Murphy; Tony Stanton; Francis G Dunn |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: The Medical clinics of North America Volume: 93 ISSN: 1557-9859 ISO Abbreviation: Med. Clin. North Am. Publication Date: 2009 May |
Date Detail:
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Created Date: 2009-05-11 Completed Date: 2009-06-09 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 2985236R Medline TA: Med Clin North Am Country: United States |
Other Details:
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Languages: eng Pagination: 681-95 Citation Subset: AIM; IM |
Affiliation:
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Cardiac Department, Stobhill Hospital, Glasgow, Scotland, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antihypertensive Agents
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therapeutic use Coronary Artery Disease / etiology Endothelium / physiopathology Hemodynamics Humans Hypertension / complications*, diagnosis, drug therapy, physiopathology Myocardial Ischemia / diagnosis, drug therapy, etiology*, physiopathology Myocardium / pathology Neurosecretory Systems Oxidative Stress Perfusion Risk Factors |
| Chemical | |
Reg. No./Substance:
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0/Antihypertensive Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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