Document Detail


Hypertension and migraine comorbidity: prevalence and risk of cerebrovascular events: evidence from a large, multicenter, cross-sectional survey in Italy (MIRACLES study).
MedLine Citation:
PMID:  21119534     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
OBJECTIVES: To estimate the prevalence of hypertension-migraine comorbidity; to determine their demographic and clinical characteristics versus patients with hypertension or migraine alone; and to see whether a history of cerebrovascular events was more common in the comorbidity group.
METHODS: The MIRACLES, multicenter, cross-sectional, survey included 2973 patients with a known diagnosis of hypertension or migraine in a general practitioner setting in Italy.
RESULTS: Five hundred and seventeen patients (17%) suffered from hypertension-migraine comorbidity, whereas 1271 (43%) suffered from hypertension only, and 1185 (40%) from migraine only. In the comorbidity group, the onset of comorbidity occurred at about 45 years of age, with migraine starting significantly later than in the migraine-only group, and hypertension significantly before than in the hypertension-only group; a familial history of both hypertension and migraine had a significantly higher frequency as compared with the hypertension and migraine group. Compared to hypertension (3.1%) and migraine (0.7%), the comorbidity group had a higher prevalence (4.4%) of history of cerebrovascular events, with an odds ratio of a predicted history of stroke/transient ischemic attack (TIA) of 1.76 [95% confidence interval (CI) 1.01-3.07] compared to the hypertension group. In patients without other recognized risk factors for stroke, stroke/TIA occurred more frequently in the comorbidity group, compared to the hypertension group. In the age range 40-49 years, prevalence of history of stroke/TIA was five-fold greater (4.8% in comorbidity vs. 0.9% in hypertension group).
CONCLUSION: This cross-sectional study indicates that the prevalence of comorbidity hypertension-migraine is substantial and that patients with comorbidity have a higher probability of history of cerebrovascular events, compared to hypertensive patients.
Authors:
Giuseppe Mancia; Enrico Agabiti Rosei; Ettore Ambrosioni; Francesco Avino; Antonio Carolei; Maurizio Daccò; Giovanni Di Giacomo; Claudio Ferri; Irene Grazioli; Gabriella Melzi; Giuseppe Nappi; Lorenzo Pinessi; Giorgio Sandrini; Bruno Trimarco; Giorgio Zanchin;
Related Documents :
2511084 - Resting heart rates in an ambulatory elderly population: an evaluation of age, sex, sym...
15151484 - Prognostic value of ambulatory blood pressure measurements for the diagnosis of hyperte...
20368244 - Short-term couplings of the cardiovascular system in pregnant women suffering from pre-...
12183854 - Non-pharmacological treatment of hypertension in women.
20649444 - The effect of argon gas pressure on ice ball size and rate of formation.
12450044 - A new rat model of chronic cerebral hypoperfusion associated with arteriovenous malform...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of hypertension     Volume:  29     ISSN:  1473-5598     ISO Abbreviation:  J. Hypertens.     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2010-12-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8306882     Medline TA:  J Hypertens     Country:  England    
Other Details:
Languages:  eng     Pagination:  309-18     Citation Subset:  IM    
Affiliation:
Department of Clinical Medicine and Prevention, University of Milano-Bicocca, St Gerardo Hospital, Monza, Milan, Italy. giuseppe.mancia@unimib.it
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Investigator
Investigator/Affiliation:
Enrico Agabiti Rosei / ; Ettore Ambrosioni / ; Rosanna Cerbo / ; Enrico Del Bene / ; Anna Ferrari / ; Claudio Ferri / ; Sergio Genco / ; Ferdinando Maggioni / ; Giuseppe Mancia / ; Lorenzo Malatino / ; Paolo Martelletti / ; Renato Nami / ; Giuseppe Nappi / ; Giovanni Palasciano / ; Maria Pia Prudenzano / ; Giorgio Sandrini / ; Paola Sarchielli / ; Bruno Trimarco / ; Massimo Volpe / ; Giorgio Zanchin / ; Fernando Di Iulio / ; Alessandro Fedele / ; Vincenzo Felli / ; Giuseppe Privitera / ; Linda Abbattista / ; Angelo Altieri / ; Michele Nicola Bellomo / ; Pasquale Bellomo / ; Daniela Bonelli / ; Giovanni Cappa / ; Emanuele Cavone / ; Angela De Bellis / ; Cosimo De Mola / ; Pietro Antonio De Renzio / ; Giuseppe Di Cecco / ; Vito Di Cosola / ; Gianfranco Di Lecce / ; Salvatore Di Paola / ; Carmine Maria Dileo / ; Francesco Ferrante / ; Alessio Gallo / ; Antonio Genchi / ; Nellina Grasso / ; Stanislao Iacobellis / ; Francesco Lampugnani / ; Antonio Lettini / ; Aristide Mancini / ; Francesco Mariani / ; Giuseppe Martinelli / ; Angela Martire / ; Antonio Mastandrea / ; Maria Antonia Miccoli / ; Gabriele Miolli / ; Natale Nicassio / ; Pierluigi Panza / ; Nicola Romito / ; Giuseppe Claudio Roselli / ; Francesco Rossi / ; Giuseppe Santoro / ; Anna Saracino / ; Francesco Savino / ; Carmelina Silvestri / ; Nicola Stucci / ; Roberto Surgo / ; Giacomo Tarì / ; Sebastiano Turchiano / ; Costantino Vigilante / ; Maria Zamparella / ; Michela Bariselli / ; Giovanni Benedetto / ; Giovanna Di Mauro / ; Carmelo Di Pietro / ; Luigi Dragone / ; Lorenzo Emiliani / ; Paolo Erba / ; Lucia Guarnera / ; Rosario Maccarrone / ; Nicola Mauro / ; Marco Palumbo / ; Salvatore Pizzo / ; Enrico Quaggiotti / ; Flavio Rigoni / ; Maurizio Romano / ; Giorgio Rondi / ; Angelo Rossi / ; Erminio Tabaglio / ; Flavio Trapelli / ; Paola Verzura / ; Gianpaola Zammarchi / ; Franco Zecchi / ; Roberto Zucchi / ; Alessio Alessi / ; Enrico Bacci / ; Sandra Bianucci / ; Franco Falorni / ; Luigi Foppa / ; Alessandro Frati / ; Jhon Luke Hili / ; Rossana Mij / ; Pasquale Negro / ; Nicoletta Niccolini / ; Cristiana Pini / ; Stefano Santangeli / ; Enzo Schirripa / ; Raoul Serni / ; Enrico Zucconi / ; Marco Bartolomucci / ; Fiorella Bontempo / ; Eugenio Calegaro / ; Maria Chiarinelli / ; Antonello Ciccarella / ; Carlo De Mattia / ; Carlo D'Innocenzo / ; Paolo Evangelista / ; Adele Giammaria / ; Mario Gizzi / ; Giacomo Laglia / ; Roberto Lupi / ; Luigi Masciovecchio / ; Antonio Nattellis / ; Americo Zugaro / ; Francesco Avino / ; Gianpaolo Barbieri / ; Giorgio Bellentani / ; Roberto Bertoli / ; M Grazia Bolognesi / ; Rossella Borghi / ; Gianpiero Bronzini / ; Marco Cassanelli / ; Ruggiero Cirsone / ; Anna Rita D'Urso / ; Maria Pina Gallina / ; Liviana Giroldi / ; Giovanni Iancu / ; Maria Pia Mai / ; Maria Manfredonia / ; Elena Nappi / ; Luca Onesti / ; Paolo Pini / ; Barbara Rubbiani / ; Rosina Sacco / ; Angela Tripodi / ; Andrea Verna / ; Claudio Zini / ; Lorenzina Aldrigo / ; Antonio Bertamini / ; Vito Bossone / ; Paolo Bovo / ; Roberto Bovo / ; Felice Bozza / ; Maurizio Danieli / ; Maria Amelia Doriguzzi / ; Giancarlo Eifu' / ; Annalisa Fragasso / ; Roberto Francheo / ; Valeria Mayellaro / ; Annalisa Moro / ; Donatella Rubiconi / ; Saverio Russo / ; Alberto Ventura / ; Romualdo Zoccali / ; Giuseppe Abbate / ; Antonino Arcangelo / ; Tommaso Battaglia / ; Gioacchino Buccoleri / ; Calogero Cardinale / ; Giuseppe Cardinale / ; Pietro D'Agati / ; Rosario D'Alessandro / ; Vittorio Di Carlo / ; Vincenzo Di Garbo / ; Matteo Favuzza / ; Emanuela Giovenco / ; Grace Liberti / ; Maria Lucia Mauceri / ; Caterina Miallo / ; Maria Assunta Progno / ; Giovanni Quartetti / ; Salvatore Scimeca / ; Sesti Enrico / ; Vito Spatafora / ; Giuseppa Spera / ; Valerio Viola / ; Giuseppe Vultaggio / ; Luigi Above / ; Giuseppe Ammirati / ; Domenico Barone / ; Pietro Brizzi / ; Stefano Callegari / ; Giovanni Cardinale / ; Gianmario Casari / ; Maurizio Coronelli / ; Maurizio Daccò / ; Danilo Deodato / ; Angelo Fortunato / ; Franco Gabba / ; Domenico Grimaldi / ; Mauro Menini / ; Antonio Musolino / ; Fabrizio Negri / ; Enrico Orlandi / ; Giovanni Pisani / ; Pietro Quattrocchi / ; Gregorio Baglioni / ; Walter Benedetti / ; Angelo Bensi / ; Mario Berardi / ; Maria Carla Birgolotti / ; Roberto Buresta / ; Emanuela Cimignoli / ; Bruno Coppini / ; Leonardo Draghini / ; Fabrizio Germini / ; Piero Grilli / ; Stefano Lindi / ; Stefano Mezzetti / ; Roberto Natali / ; Valerio Pannacci / ; Damiano Parretti / ; Stefania Petrelli / ; Francesco Rossi / ; Tiziano Scarponi / ; Valerio Sgrelli / ; Maria Antonietta Surace / ; Adelaide Susta / ; Luca Tedeschi / ; Alessandro Urbani / ; Salvatore Bennardo / ; Rocco Bitetti / ; Rosario Burgio / ; Giuseppe Caccamo / ; Carla Cottonaro / ; Giovanni Di Giacomo / ; Salvatore Di Pasquale / ; Salvatore Di Stefano / ; Giuseppe Drago / ; Giorgio Gurrieri / ; Francesco La Rosa / ; Bernardo La Terra Bella / ; Giovanni Ottaviano / ; Vincenzo Ottaviano / ; Giorgio Ruta / ; Flavio Sortino / ; Francesco Tidona / ; Alessandro Tumino / ; Giovanni Tumino / ; Mario Tumino / ; Giovanni Vitale / ; Roberto Francesco Maria Zelante / ; Amedeo Annibali / ; Luca Antognoli / ; Pietro Antonelli / ; Roberto Etilio Arcadi / ; Antonio Bartolini / ; Carla Bruschelli / ; Alberto Calvieri / ; Paola Domeniconi / ; Marzio Fiumana / ; Fabio Frittaion / ; Marina Lazzaro / ; Fabiola Leardi / ; Marina Leoni / ; Gianfranco Marini / ; Gallieno Marri / ; Raffaella Massari / ; Nicoletta Mazzei / ; Bonaventura Mocci / ; Mauro Mocci / ; Alessandra Morelli / ; Giulio Nati / ; Sebastiano Orifici / ; Maria Luisa Paoletti / ; Maurizio Parisi / ; Massimo Pergolini / ; Italo Polce / ; Stefano Roberto Polce / ; Paolo Questino / ; Francesco Rossiello / ; Massimo Sabatini / ; Tiziana Volpe / ; Mario Agnello / ; Luciano Antonaci / ; Paolo Antonucci / ; Renato Avaltroni / ; Natale Barbaro / ; Luigi Bartolone / ; Maria Alessandra Bertini / ; Pierfrancesco Blasi / ; Vittoria Bruziches / ; Paolo Cannata / ; Antonietta Cannone / ; Carlo Capuano / ; Marco Carbonetti / ; Sergio Cianfriglia / ; Renato Fanelli / ; Francesco Fazi / ; Stefano Gambioli / ; Mauro Giannini / ; Michele Giannone / ; Gabriele Guerriero / ; Luigi Lanza / ; Corrado Latino / ; Marina Leporelli / ; Giovanni Maresca / ; Giorgio Matzuzzi / ; Luigi Milani / ; Amedeo Mocci / ; Luigi Muccichini / ; Francesco Oliva / ; Maria Antonietta Palange / ; Carmelo Pratticò / ; Maurizio Re / ; Emanuele Sagoni / ; Sandro Salciccia / ; Alberta Sciarretta / ; Cinzia Silvi / ; Fortunata Tranò / ; Paola Tripiciano / ; Antonio Troccoli / ; Stefano Troysi / ; Salvatore Ansaldi / ; Fazio Anselmi / ; Claudio Bianchini / ; Flavio Carletti / ; Rugero De Michelis / ; Enzo De Risi / ; Sebastiano Faglia / ; Lelio Fracassi / ; Andrea Franci / ; Giancarlo Lenzi / ; Mario Loretti / ; Fabio Marchetti / ; Giuseppe Marrelli / ; Andrea Martellini / ; Anna Moretti / ; Luana Pieragalli / ; Paola Sani / ; Giuseppe Scibilia / ; Paolo Turillazzi /

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Are angiotensin-converting enzyme inhibitors and angiotensin receptor blockers safe in pregnancy: a ...
Next Document:  Spontaneous intracranial hypotension without intracranial hypotension.