Document Detail

Hypertension and its management in the elderly.
MedLine Citation:
PMID:  20006792     Owner:  NLM     Status:  MEDLINE    
Many trials focused on cardiovascular outcomes demonstrate that reduction in blood pressure to levels below 140/90 mm Hg reduce cardiovascular events including stroke and myocardial infarction. There are very few such trials, however, in the elderly cohort, especially among those aged 70 and older. In the few outcome trials that have been completed in this older age group, systolic blood pressures in the range between 140 and 149 mm Hg demonstrate a clear reduction in cardiovascular events. Moreover, among the subgroup that has a vasculature that allows a systolic pressure to go below 140 mm Hg without cognitive side effects, ie, somnolence, memory loss, etc, does even better than those whose blood pressures are in the 140 to 149 mm Hg range. Thus, titration of systolic blood pressure goals in the elderly should strive for a goal of less than 140 mm Hg, and if not achievable without side effects, compromise to below 150 mm Hg.
Basil O Burney; George L Bakris
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Seminars in nephrology     Volume:  29     ISSN:  1558-4488     ISO Abbreviation:  Semin. Nephrol.     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2009-12-17     Completed Date:  2010-04-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8110298     Medline TA:  Semin Nephrol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  604-9     Citation Subset:  IM    
Department of Medicine, Hypertensive Diseases Unit, University of Chicago Pritzker School of Medicine, Chicago, IL 60637, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Aging / physiology*
Antihypertensive Agents / therapeutic use*
Diet, Carbohydrate-Restricted
Diet, Reducing
Hypertension / drug therapy*,  physiopathology*
Risk Reduction Behavior*
Reg. No./Substance:
0/Antihypertensive Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Identifying advanced glycation end products as a major source of oxidants in aging: implications for...
Next Document:  Disorders of lipid metabolism and chronic kidney disease in the elderly.