Document Detail


Hypertension and its correlates in two communities of dissimilar genetic ancestry in Sikkim, India.
MedLine Citation:
PMID:  19852677     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Hypertension has emerged as a major health risk among adults and the elderly in India. In spite of sharing similar physical and cultural environments, group level cultural variability and distinct genetic ancestry may result in differences in patterns of hypertension prevalence. AIM: The present study investigates the relationships between socio-economic, lifestyle and anthropometric variables and hypertension in two communities (Rai and Bhutia) of Sikkim. Both groups live in a similar ecological setting and are exposed to forces of modernization of almost equal magnitude. SUBJECTS AND METHODS: The study sample consists of 582 Rais and 315 Bhutias. Information on socio-demographic characteristics, substance uses and other lifestyle variables were collected through relevant pre-tested questionnaires. Anthropometric measurements were taken following standard methods. Three consecutive blood pressure measurements were taken and averaged for analysis. RESULTS: The results of covariance analyses show that ethnicity is not a significant covariate of either systolic or diastolic blood pressure. Use of tobacco and alcohol consumption, level of education and activity patterns were found to be significant correlates of hypertension. The diagnostic ability of waist circumference is found to be better than body mass index for assessment of risk of hypertension among the present study populations. CONCLUSIONS: Lifestyle factors more than ethnicity and socio-economic factors contribute to the development of hypertension in these populations. Based on the results of this study, we would suggest that a sustainable increase in physical activity and reduction in alcohol consumption would be helpful in the proper management of hypertension for both groups.
Authors:
Shailendra Kumar Mishra; Sovanjan Sarkar; Susmita Mukhopadhyay; Barun Mukhopadhyay
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Annals of human biology     Volume:  37     ISSN:  1464-5033     ISO Abbreviation:  Ann. Hum. Biol.     Publication Date:    2010 Jan-Feb
Date Detail:
Created Date:  2009-12-08     Completed Date:  2010-02-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0404024     Medline TA:  Ann Hum Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  23-43     Citation Subset:  IM    
Affiliation:
Biological Anthropology Unit, Indian Statistical Institute, Kolkata 700108, India.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Body Mass Index
Cross-Sectional Studies
Diastole
Educational Status
Female
Humans
Hypertension / ethnology,  etiology*,  genetics
Logistic Models
Male
Middle Aged
ROC Curve
Socioeconomic Factors
Systole
Waist Circumference

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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