Document Detail


Hypertension-induced cardiac damage in children and adolescents.
MedLine Citation:
PMID:  10490869     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Blood pressure elevation has numerous sequelae, including myocardial infarction, stroke, congestive heart failure, end-stage renal disease, and peripheral vascular disease in adults. The impact of blood pressure elevation on target organs in children and adolescents has been less well studied. The most useful measure of cardiac effects of hypertension is the echocardiogram. Studies have now defined normal standards for left ventricular mass in young patients. In order to account for differences in body size, it is most appropriate to use left ventricular mass divided by the individual s height raised to a power of 2.7. It has been demonstrated that there is a high prevalence of left ventricular hypertrophy in adolescents with essential hypertension. Some adolescents develop severe hypertrophy and abnormal left ventricular geometry, even to a degree that would be associated with increased risk of cardiovascular disease morbidity in an adult patient. Further research is needed to better evaluate the regression of left ventricular hypertrophy. Clinicians should assess left ventricular mass index in the evaluation of pediatric patients with hypertension.
Authors:
S R Daniels
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Blood pressure monitoring     Volume:  4     ISSN:  1359-5237     ISO Abbreviation:  Blood Press Monit     Publication Date:    1999 Jun-Aug
Date Detail:
Created Date:  1999-12-01     Completed Date:  1999-12-01     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9606438     Medline TA:  Blood Press Monit     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  165-70     Citation Subset:  IM    
Affiliation:
Division of Cardiology, Department of Pediatrics, University of Cincinnati College of Medicine and the Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA. sdaniels@chmcc.org
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Blood Pressure*
Child
Child, Preschool
Heart / physiopathology*
Heart Diseases* / etiology,  physiopathology
Humans
Hypertension* / complications,  pathology,  physiopathology
Hypertrophy, Left Ventricular
Ventricular Function, Left

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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