Document Detail

Hypertension in women.
MedLine Citation:
PMID:  11095160     Owner:  NLM     Status:  MEDLINE    
Hypertension in women has received less attention than hypertension in men, and the major controlled trials of antihypertensive therapy have been carried out in populations made up predominantly of and have emphasised outcomes in men. Recently it has been recognised that women develop high blood pressure, particularly systolic hypertension, at an increased rate as they age, and that this age-related blood pressure increase is exaggerated by the menopause. The age-related rise in blood pressure, particularly systolic blood pressure and pulse pressure, contributes substantially to the age-related increase in risk of heart attack, heart failure, and stroke in middle-aged and elderly women. This article reviews aspects of hypertension epidemiology, pathophysiology, diagnosis and treatment that are important to women's health with particular emphasis on important concomitant cardiovascular disease risk factors such as type 2 diabetes and the menopause. The role of ovarian hormones and their withdrawal in the pathogenesis of hypertension and related target organ damage is considered, as are the results of drug treatment of high blood pressure in women. Blood pressure in pregnancy is discussed in a separate article by Broughton-Pipkin and Roberts.
T Rosenthal; S Oparil
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of human hypertension     Volume:  14     ISSN:  0950-9240     ISO Abbreviation:  J Hum Hypertens     Publication Date:    2000 Oct-Nov
Date Detail:
Created Date:  2001-02-07     Completed Date:  2001-03-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8811625     Medline TA:  J Hum Hypertens     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  691-704     Citation Subset:  IM    
Chorley Hypertension Institute, Chaim Sheba Medical Center, Tel Hashomer, Israel.
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MeSH Terms
Age Factors
Blood Pressure
Contraceptives, Oral / adverse effects
Gonadal Steroid Hormones / metabolism
Hypertension* / epidemiology,  etiology,  metabolism,  physiopathology
Menstrual Cycle / metabolism
Risk Factors
Reg. No./Substance:
0/Contraceptives, Oral; 0/Gonadal Steroid Hormones

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