| Hypertension in women: the role of progesterone and aldosterone. | |
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MedLine Citation:
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PMID: 20443718 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The age-related course of blood pressure and its gender-related difference, as well as the incidence of hypertension, have been the subject of multiple experimental, clinical and epidemiological studies over the past decades. The role of the sex hormones estradiol and testosterone within this gender dimorphism has been investigated without conclusive results. In this review, we provide background information on the gender difference in blood pressure, describe the impact of progesterone and aldosterone, and discuss the pathophysiology of aldosteronism as well as the potential role of drospirenone as a gender-specific agent for the prevention and treatment of hypertension and for cardiovascular protection. |
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Authors:
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E Boschitsch; S Mayerhofer; D Magometschnigg |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Climacteric : the journal of the International Menopause Society Volume: 13 ISSN: 1473-0804 ISO Abbreviation: Climacteric Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-06-14 Completed Date: 2010-09-23 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9810959 Medline TA: Climacteric Country: England |
Other Details:
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Languages: eng Pagination: 307-13 Citation Subset: IM |
Affiliation:
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Klimax Menopause Clinic, Linke Wienzeile 56, Vienna, Austria. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aldosterone / adverse effects, physiology* Aldosterone Antagonists / therapeutic use Androstenes / administration & dosage, therapeutic use Animals Cardiovascular Diseases / etiology Diet, Sodium-Restricted Estradiol / administration & dosage Estrogens / adverse effects, pharmacology, physiology Female Humans Hypertension* / complications, drug therapy, prevention & control Middle Aged Natriuresis Progesterone / physiology* Progesterone Congeners / adverse effects, pharmacology Renin-Angiotensin System / drug effects, physiology Risk Factors Sex Characteristics |
| Chemical | |
Reg. No./Substance:
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0/Aldosterone Antagonists; 0/Androstenes; 0/Estrogens; 0/Progesterone Congeners; 50-28-2/Estradiol; 52-39-1/Aldosterone; 57-83-0/Progesterone; 67392-87-4/drospirenone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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