Document Detail

Hypertension in relation to musculoskeletal disorders.
MedLine Citation:
PMID:  1221926     Owner:  NLM     Status:  MEDLINE    
Generalized osteoarthrosis was found to be significantly more common in older males with high than with low diastolic blood pressure. The excess of osteoarthrosis in those with hypertension was mainly in the hips, knees, carpometacarpal and metacarpophalangeal joints, and was independent of obesity in the hypertensive group. It was not associated with a higher cholesterol or uric acid level in the serum. Radiological evidence of avascular necrosis was present in 36% of males with osteoarthrosis of the hips and diastolic blood pressure above 100 mmHg, in 20% with a diastolic pressure of 81-100 mmHg, but was found in none of those with osteoarthrosis and blood pressure of 80 mmHg or below. Only those with osteoarthrosis and a diastolic pressure above 100 mmHg had significantly more avascular necrosis that expected. Osteoarthrosis of the knee in female was more frequent in the hypertensive groups independent of obesity. It is concluded that vascular disorders are involved in this form of generalized osteoarthrosis.
J S Lawrence
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of the rheumatic diseases     Volume:  34     ISSN:  0003-4967     ISO Abbreviation:  Ann. Rheum. Dis.     Publication Date:  1975 Oct 
Date Detail:
Created Date:  1976-06-02     Completed Date:  1976-06-02     Revised Date:  2010-09-07    
Medline Journal Info:
Nlm Unique ID:  0372355     Medline TA:  Ann Rheum Dis     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  451-56     Citation Subset:  IM    
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MeSH Terms
Blood Pressure
Cholesterol / blood
Hypertension / complications*
Intervertebral Disk / physiopathology
Knee Joint / physiopathology
Osteoarthritis / blood,  complications,  epidemiology
Uric Acid / blood
Wrist Joint / physiopathology
Reg. No./Substance:
57-88-5/Cholesterol; 69-93-2/Uric Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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