| Hypertension in pregnancy. | |
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MedLine Citation:
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PMID: 8199715 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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From the clinical point of view proteinuric hypertension or preeclampsia is the most important form of hypertension in pregnancy and carries the greatest risks for mother and foetus. The syndrome 'preeclampsia' differs from other types of hypertension and its effects on mother and foetus are not clearly benefited by lowering the blood pressure with drugs. The characteristic morphological changes and altered vascular reactivity which develop in preeclampsia commence at about 14 weeks gestation, long before hypertension or proteinuria appear. Many abnormalities in coagulation mechanisms appear in preeclampsia and some may play an important part in pathogenesis. Increased plasminogen activator inhibitor may play a key role. Antihypertensive drugs used during pregnancy may reduce foetal mortality and the incidence of preeclampsia. Calcium supplementation and aspirin may reduce the incidence of preeclampsia in high risk subjects. Heparin and dipyridamole may reduce the risk of preeclampsia in high risk patients with renal disease. |
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Authors:
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P Kincaid-Smith |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Blood pressure Volume: 3 ISSN: 0803-7051 ISO Abbreviation: Blood Press. Publication Date: 1994 Mar |
Date Detail:
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Created Date: 1994-07-01 Completed Date: 1994-07-01 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9301454 Medline TA: Blood Press Country: NORWAY |
Other Details:
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Languages: eng Pagination: 18-23 Citation Subset: IM |
Affiliation:
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Department of Pathology, University of Melbourne, Parkville, Victoria, Australia. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antihypertensive Agents
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therapeutic use Female Forecasting Humans Hypertension* / complications, drug therapy Pre-Eclampsia / drug therapy, etiology, prevention & control Pregnancy Pregnancy Complications, Cardiovascular* / drug therapy Terminology as Topic |
| Chemical | |
Reg. No./Substance:
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0/Antihypertensive Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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