Document Detail


Hypertension in pregnancy.
MedLine Citation:
PMID:  16157076     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Hypertension in pregnancy contributes significantly to both maternal and neonatal morbidity and mortality. Among different forms of pregnancy-associated hypertension, preeclampsia-eclampsia has the highest impact on morbidity and mortality. Chronic hypertension may result in preterm and small for gestational age infants, even when it is mild-to-moderate. Chronic hypertension is a risk factor for superimposed preeclampsia and results in higher rates of adverse outcome. Preeclampsia is a multisystemic disease that is thought to be initiated by abnormalities in placental perfusion and endothelial dysfunction, ultimately resulting in multiorgan failure. Preeclampsia is more common in women of minority ethnicity who are socioeconomically disadvantaged. Pharmacologic therapy for hypertensive disorders in pregnancy is limited by concerns regarding the safety of both mother and fetus. Although treatment of severe hypertension is not debated, there is no consensus on the rationale for pharmacologic therapy of mild-to-moderate hypertension in pregnancy.
Authors:
Maryann Mugo; Gurushankar Govindarajan; L Romayne Kurukulasuriya; James R Sowers; Samy I McFarlane
Related Documents :
15121616 - Ketanserin in women with chronic hypertension and underlying thrombophilia.
7905426 - The role of complement in pregnancy-induced hypertensive disease.
9988826 - Preeclampsia: an excessive maternal inflammatory response to pregnancy.
8904056 - Low dose aspirin in prevention of pregnancy-induced hypertension in primigravidae at th...
14551026 - Acog committee opinion number 288, october 2003: professional liability and gynecology-...
20200806 - Upper respiratory tract infection during pregnancy: is it associated with adverse perin...
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current hypertension reports     Volume:  7     ISSN:  1522-6417     ISO Abbreviation:  Curr. Hypertens. Rep.     Publication Date:  2005 Oct 
Date Detail:
Created Date:  2005-09-13     Completed Date:  2006-01-27     Revised Date:  2006-07-12    
Medline Journal Info:
Nlm Unique ID:  100888982     Medline TA:  Curr Hypertens Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  348-54     Citation Subset:  IM    
Affiliation:
University of Missouri-Columbia and the Harry S. Truman Memorial Veterans Administration Hospital, One Hospital Drive, Columbia, MO 65212, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Antineoplastic Agents / therapeutic use*
Chronic Disease
Female
Humans
Hypertension / diagnosis,  physiopathology,  therapy*
Pregnancy
Pregnancy Complications, Cardiovascular / diagnosis,  physiopathology,  therapy*
Chemical
Reg. No./Substance:
0/Antineoplastic Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  The role of aldosterone antagonists in the management of resistant hypertension.
Next Document:  Should the target for blood pressure control specify both a systolic and a diastolic component?