Document Detail


Hypertension in pregnancy: is it time for a new approach to treatment?
MedLine Citation:
PMID:  22573074     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Hypertensive disorders represent major causes of pregnancy-related maternal mortality worldwide. The current definition and treatment recommendations for elevated blood pressure (BP) during pregnancy in the United States have remained unchanged for many years, unlike the recommendations for hypertension treatment in the general population. Clinical studies have provided convincing evidence that women with hypertensive pregnancy disorders are at both immediate and long-term risk for cardiovascular complications; these findings suggest that consideration be given to lowering the presently recommended BP thresholds, both for the initiation of therapy and for therapeutic targets, and to simplifying the approach to the management of elevated BP in pregnancy. This review focuses on the current treatment strategies for hypertensive pregnancy disorders, new developments in the field of hypertension, in general, and in pregnant patients, in particular, and their potential impact on contemporary BP goals and the use of specific antihypertensive medications in pregnancy.
Authors:
Marvin Moser; Catherine M Brown; Carl H Rose; Vesna D Garovic
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of hypertension     Volume:  30     ISSN:  1473-5598     ISO Abbreviation:  J. Hypertens.     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-05-10     Completed Date:  2012-08-31     Revised Date:  2013-08-27    
Medline Journal Info:
Nlm Unique ID:  8306882     Medline TA:  J Hypertens     Country:  England    
Other Details:
Languages:  eng     Pagination:  1092-100     Citation Subset:  IM    
Affiliation:
Department of Medicine/Cardiology, Yale University School of Medicine, New Haven, Connecticut, USA.
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MeSH Terms
Descriptor/Qualifier:
Antihypertensive Agents / therapeutic use
Blood Pressure
Female
Humans
Hypertension / complications,  drug therapy*,  physiopathology
Pregnancy
Pregnancy Complications, Cardiovascular / drug therapy*,  physiopathology
Grant Support
ID/Acronym/Agency:
K08 HD051714/HD/NICHD NIH HHS; K08HD051714/HD/NICHD NIH HHS
Chemical
Reg. No./Substance:
0/Antihypertensive Agents
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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