Document Detail

Hypertension in pregnancy: an emerging risk factor for cardiovascular disease.
MedLine Citation:
PMID:  17957198     Owner:  NLM     Status:  MEDLINE    
Increasing evidence indicates that hypertension in pregnancy is an under-recognized risk factor for cardiovascular disease (CVD). Compared with women who have had normotensive pregnancies, those who are hypertensive during pregnancy are at greater risk of cardiovascular and cerebrovascular events and have a less favorable overall risk profile for CVD years after the affected pregnancies. One factor that might underlie this relationship is that hypertensive disorders of pregnancy (pre-eclampsia, in particular) and CVD share several common risk factors (e.g. obesity, diabetes mellitus and renal disease). Alternatively, hypertension in pregnancy could induce long-term metabolic and vascular abnormalities that might increase the overall risk of CVD later in life. In both cases, evidence regarding risk-reduction interventions specific to women who have had hypertensive pregnancies is lacking. While awaiting results of large-scale studies, hypertensive disorders of pregnancy should be screened for during assessment of a woman's overall risk profile for CVD. Women at high risk must be monitored closely for conventional risk factors that are common to both CVD and hypertensive disorders of pregnancy and treated according to current evidence-based national guidelines.
Vesna D Garovic; Suzanne R Hayman
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Nature clinical practice. Nephrology     Volume:  3     ISSN:  1745-8331     ISO Abbreviation:  -     Publication Date:  2007 Nov 
Date Detail:
Created Date:  2007-10-24     Completed Date:  2007-11-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101261800     Medline TA:  Nat Clin Pract Nephrol     Country:  England    
Other Details:
Languages:  eng     Pagination:  613-22     Citation Subset:  IM    
Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, 200 First Street South West, Rochester, MN 55905, USA.
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MeSH Terms
Coronary Disease / epidemiology*
Hypertension, Pregnancy-Induced / epidemiology*
Pre-Eclampsia / epidemiology*
Risk Factors
Stroke / epidemiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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