Document Detail

Hypertension in pregnancy: a comprehensive update.
MedLine Citation:
PMID:  20539101     Owner:  NLM     Status:  MEDLINE    
Hypertensive disorders of pregnancies remain a central public health concern throughout the world, and are a major cause of maternal mortality in the developing world. Although treatment options have not significantly changed in recent years, insight on the pathogenesis of preeclampsia/eclampsia has been remarkable. With improved animal models of preeclampsia and large-scale human trials, we have embarked upon a new era where angiogenic biomarkers based on mechanism of disease can be designed to assist in early diagnosis and treatment. There is also a growing recognition of how elusive the diagnosis of eclampsia can be, especially in the postpartum period. Proper treatment of these patients depends heavily on the correct diagnosis, especially by the emergency physician. Finally, large epidemiologic studies have revealed that preeclampsia, once thought to be a self-limited entity, now appears to portend real damage to the cardiovascular and other organ systems in the long term. This review will present the latest update on our understanding of the various hypertensive disorders of pregnancies and their treatment options.
Belinda Jim; Shuchita Sharma; Tewabe Kebede; Anjali Acharya
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Cardiology in review     Volume:  18     ISSN:  1538-4683     ISO Abbreviation:  Cardiol Rev     Publication Date:    2010 Jul-Aug
Date Detail:
Created Date:  2010-06-11     Completed Date:  2010-10-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9304686     Medline TA:  Cardiol Rev     Country:  United States    
Other Details:
Languages:  eng     Pagination:  178-89     Citation Subset:  IM    
Renal Division, Department of Medicine, Jacobi Medical Center, Bronx, NY 10461, USA.
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MeSH Terms
Antihypertensive Agents / therapeutic use
Biological Markers / metabolism
Chronic Disease
Delivery, Obstetric / methods
Dietary Supplements
Hypertension / classification,  diagnosis*,  metabolism,  physiopathology,  therapy*
Hypertension, Pregnancy-Induced / diagnosis,  metabolism,  physiopathology,  therapy
Podocytes / metabolism
Postpartum Period
Pregnancy Complications, Cardiovascular / classification,  diagnosis*,  metabolism,  physiopathology,  therapy*
Treatment Outcome
Reg. No./Substance:
0/Antihypertensive Agents; 0/Biological Markers

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