Document Detail

Hypertension in the elderly.
MedLine Citation:
PMID:  20872373     Owner:  NLM     Status:  MEDLINE    
Hypertension is a common problem in the elderly. Its prevalence is currently 60%-80%, but it is estimated that it will increase with the projected population growth of older people aged more than 65 years. Hypertension is a major cardiovascular risk factor due to the well-known continuous relationship between high blood pressure, stroke and cardiovascular (CV) mortality in all age groups. Because of the expected increasing proportion of older people, a further increase in CV and renal complications of hypertension in the next few decades can be predicted. In the elderly, systolic blood pressure increases because of arterial stiffness produced by structural alterations of arterial wall occurring with aging. On the other hand, in people aged 60 years and over, diastolic blood pressure remains unchanged or decreases. Isolated systolic hypertension and high pulse pressure are thus prevalent, and are important risk factors for stroke, coronary heart disease and all-cause mortality in the elderly and very elderly. The efficacy of therapy in older patients with systolic and diastolic hypertension or with isolated systolic hypertension, in terms of reduction of cardiovascular morbility and mortality, have been widely confirmed by many controlled and randomized clinical trials.
Antonio Del Giudice; Giovanni Pompa; Filippo Aucella
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of nephrology     Volume:  23 Suppl 15     ISSN:  1121-8428     ISO Abbreviation:  J. Nephrol.     Publication Date:    2010 Sep-Oct
Date Detail:
Created Date:  2010-09-27     Completed Date:  2010-12-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9012268     Medline TA:  J Nephrol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  S61-71     Citation Subset:  IM    
IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Foggia, Italy.
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MeSH Terms
Age Factors
Aged, 80 and over
Antihypertensive Agents / therapeutic use
Arteries / physiopathology
Blood Pressure* / drug effects
Blood Pressure Determination
Cardiovascular Diseases / epidemiology,  physiopathology,  prevention & control
Geriatric Assessment
Health Services for the Aged
Hypertension / diagnosis,  drug therapy,  epidemiology,  physiopathology*
Middle Aged
Practice Guidelines as Topic
Treatment Outcome
Reg. No./Substance:
0/Antihypertensive Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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