Document Detail

Hypertension in pediatric patients with renal scarring in association with vesicoureteral reflux.
MedLine Citation:
PMID:  23153949     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To examine the reflux nephropathy rate and severity as well as the hypertension rate in pediatric patients with vesicoureteral reflux (VUR).
METHODS: The study included 240 patients with VUR. Renal scarring (RS) was demonstrated by renal parenchymal examination using technetium-99m-labeled dimercaptosuccinic acid (99mTc-DMSA) scintigraphy. Office measurements of arterial blood pressure and ambulatory blood pressure monitoring (ABPM) of VUR patients were done during the follow-up period.
RESULTS: Follow-up was a mean duration of 24 months. Rates of RS and hypertension increased parallel to increases in the degree of VUR. A gradual elevation in hypertension rates was evident during the follow-up period. All patients with hypertension had RS. Severe RS in 56 patients was associated with increasing blood pressure readings by 24-hour ABPM or office measurements in 19 patients (33.9%). ABPM measurements enabled us to detect additional patients compared with office measurements alone.
CONCLUSION: Hypertension is a serious complication in children with reflux nephropathy and is associated with the severity of RS and VUR grade. ABPM seems to be superior over office measurements of blood pressure in identifying patients with hypertension.
Kibriya Fidan; Yasar Kandur; Bahar Buyukkaragoz; Umit Ozgur Akdemir; Oguz Soylemezoglu
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Publication Detail:
Type:  Journal Article     Date:  2012-11-13
Journal Detail:
Title:  Urology     Volume:  81     ISSN:  1527-9995     ISO Abbreviation:  Urology     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2012-12-31     Completed Date:  2013-03-22     Revised Date:  2014-01-07    
Medline Journal Info:
Nlm Unique ID:  0366151     Medline TA:  Urology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  173-7     Citation Subset:  IM    
Copyright Information:
Copyright © 2013 Elsevier Inc. All rights reserved.
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MeSH Terms
Blood Pressure
Blood Pressure Monitoring, Ambulatory*
Chi-Square Distribution
Child, Preschool
Cicatrix / complications,  physiopathology*,  radionuclide imaging
Follow-Up Studies
Hypertension / complications,  diagnosis,  physiopathology*
Kidney / pathology
Severity of Illness Index
Sex Factors
Vesico-Ureteral Reflux / complications,  physiopathology*
Young Adult
Comment In:
Aktuelle Urol. 2013 Nov;44(6):421-2   [PMID:  24281925 ]
J Urol. 2013 Nov;190(5):1893   [PMID:  24120812 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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