Document Detail


Hypertension and common complications --analysis of the ambulatory treatment cost.
MedLine Citation:
PMID:  20377054     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIM: Retrospective analysis of the prescribing practice and cost of ambulatory treatment of hypertension and its common complications--heart failure, sequelae of cerebrovascular disease, and angina pectoris. METHODS: Analysis of 3,240 reimbursable ambulatory prescriptions for hypertension, heart failure, sequelae of cerebrovascular disease and angina pectoris according to the complexity of the therapy and frequency of the prescribed medicines. Modeling and calculation of the expected monthly cost for outpatient therapy by using the "decision tree model". Sensitivity analysis is performed within the +/- 30% interval. RESULTS: 65% of the prescription were for the hypertension, and 35% for the observed complications. 1,297 prescriptions for hypertension include one medicine, 647 include two medicines, and only 8% of prescriptions were for three medicines. ACE inhibitors have been prescribed in 41% of all hypertension prescriptions, followed by beta-blockers (19%), Ca channel blockers (16%), diuretics (15%) etc. The prescriptions for hypertension complications are more diverse as therapeutic groups. The expected monthly cost of prescribed medicines per patient with hypertension alone is 6.90 Euro and in case of complications it is 10.71 Euro according to the prevalence of the complexity of therapy, and weighted monthly cost of medicines. The overall ambulatory cost is expected to be around 148 million Euro per year for near 1.5 million patients with 44% reimbursement. The cost of the therapy is sensitive more to changes in the medicine's prices than to its complexity. CONCLUSION: This study is a first step in providing information for evidence-based cost containment measures or policy decisions at ambulatory level in Bulgaria and for the assessment of the share of complications' therapy on the overall hypertension cost.
Authors:
Anna D Ivanova; Guenka I Petrova
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Central European journal of public health     Volume:  17     ISSN:  1210-7778     ISO Abbreviation:  Cent. Eur. J. Public Health     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2010-04-09     Completed Date:  2010-04-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9417324     Medline TA:  Cent Eur J Public Health     Country:  Czech Republic    
Other Details:
Languages:  eng     Pagination:  223-30     Citation Subset:  IM    
Affiliation:
Department of Social Pharmacy, Faculty of Pharmacy, Medical University, Sofia, Bulgaria. an5dar@yahoo.co.uk
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MeSH Terms
Descriptor/Qualifier:
Ambulatory Care / economics*
Angina Pectoris / drug therapy,  economics
Antihypertensive Agents / economics*,  therapeutic use*
Cardiovascular Agents / economics,  therapeutic use
Cardiovascular Diseases / drug therapy,  economics*
Decision Trees
Drug Therapy, Combination
Drug Utilization
Heart Failure / drug therapy,  economics
Humans
Hypertension / drug therapy*,  economics*
Physician's Practice Patterns / economics
Prescription Fees
Retrospective Studies
Chemical
Reg. No./Substance:
0/Antihypertensive Agents; 0/Cardiovascular Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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