Document Detail

Hypertension and cognitive performance in African Americans with Alzheimer disease.
MedLine Citation:
PMID:  15753433     Owner:  NLM     Status:  MEDLINE    
The authors examined the relationship between hypertension and cognitive performance in 34 African-American patients with probable Alzheimer disease. Multiple regression analyses indicated that hypertension was associated with poorer overall performance on the Mattis Dementia Rating Scale, particularly the Initiation/Perseveration and Conceptualization subscales, after controlling for gender, age, and education. The findings suggest that African-American patients with hypertension exhibit greater cognitive impairment, possibly reflecting executive dysfunction.
F C Goldstein; A V Ashley; L J Freedman; L Penix; J J Lah; J Hanfelt; A I Levey
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Neurology     Volume:  64     ISSN:  1526-632X     ISO Abbreviation:  Neurology     Publication Date:  2005 Mar 
Date Detail:
Created Date:  2005-03-08     Completed Date:  2006-02-09     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0401060     Medline TA:  Neurology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  899-901     Citation Subset:  AIM; IM    
Department of Neurology, Emory University School of Medicine, 1841 Clifton Road, N.E., Atlanta, GA 30329, USA.
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MeSH Terms
African Americans / ethnology*,  genetics
Age Factors
Aged, 80 and over
Alzheimer Disease / complications*,  ethnology,  psychology
Cholinesterase Inhibitors / therapeutic use
Cognition Disorders / complications*,  ethnology,  psychology
Depression / complications
Educational Status
Genetic Predisposition to Disease / ethnology*
Hypertension / complications*,  ethnology,  psychology
Middle Aged
Neuropsychological Tests
Regression Analysis
Sex Factors
Grant Support
Reg. No./Substance:
0/Cholinesterase Inhibitors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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