Document Detail


Hypertension, beta-adrenoceptor blocking agents and exercise.
MedLine Citation:
PMID:  7911791     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Studies have shown that regular exercise may contribute to a lowering of blood pressure in hypertensive patients. The extent of the blood pressure reduction, however, appears to be limited and will in most cases be insufficient to normalize blood pressure in these patients. Therefore, many of the physically active hypertensive patients will be treated with antihypertensive agents. Treatment of physically active patients with uncomplicated hypertension with beta-blocking agents has disadvantages, since these agents reduce exercise capacity and may affect trainability in a negative way. beta 1-Selective blockers have less pronounced effects than beta 1+2-blockers and may be acceptable for some patients. In patients with very high systolic blood pressures during exercise and those with impaired oxygen delivery to the heart during exercise beta 1-selective blockers may have advantages over other antihypertensive agents, since they very effectively reduce systolic blood pressure and heart rate during exercise.
Authors:
M A van Baak
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  International journal of sports medicine     Volume:  15     ISSN:  0172-4622     ISO Abbreviation:  Int J Sports Med     Publication Date:  1994 Apr 
Date Detail:
Created Date:  1994-07-21     Completed Date:  1994-07-21     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8008349     Medline TA:  Int J Sports Med     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  112-5     Citation Subset:  IM    
Affiliation:
Department of Human Biology, University of Limburg, Maastricht, The Netherlands.
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MeSH Terms
Descriptor/Qualifier:
Adrenergic beta-Antagonists / therapeutic use*
Blood Pressure / drug effects
Exercise / physiology*
Heart Rate / drug effects
Humans
Hypertension / drug therapy*,  physiopathology*
Chemical
Reg. No./Substance:
0/Adrenergic beta-Antagonists

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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