Document Detail


Hypertension awareness, treatment, and control in chronic kidney disease.
MedLine Citation:
PMID:  18374693     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Hypertension prevalence, awareness, treatment, and blood pressure control rates in the population with chronic kidney disease are limited. The objective of this study was to determine the state of blood pressure control in patients with chronic kidney disease. METHODS: This is a cross-sectional analysis of data of participants with chronic kidney disease from the Kidney Early Evaluation Program. The Kidney Early Evaluation Program is a national-based health screening program for individuals at high risk for kidney disease conducted in 49 states and the District of Columbia. Of 55,220 adults with kidney disease, 10,813 completed information for demographic and medical characteristics used in the analysis. Predictors of blood pressure control were assessed using multiple logistic regression analysis. RESULTS: Hypertension prevalence, awareness, and treatment proportions in the screened cohort were high (86.2%, 80.2%, and 70.0%, respectively), but blood pressure control rates were low (13.2%). These proportions increased with advancing stage of kidney disease. Elevated systolic blood pressure accounted for the majority of inadequate control. Male gender (odds ratio [OR] 0.86; 95% confidence interval [CI], 0.75-0.99), non-Hispanic black race (OR 0.76; 95% CI, 0.65-0.89), and body mass index of 30 kg/m(2) or more (OR 0.83; 95% CI, 0.73-0.94) were inversely related with blood pressure control. Those with stage 3 kidney disease were more likely to have blood pressure at goal than those with stage 1 kidney disease (OR 2.08; 95% CI, 1.55-2.80). CONCLUSION: We conclude that despite increased awareness and treatment of hypertension, control rates in these participants are poor. This poor control rate centers around elevated systolic pressure in people who are obese, non-Hispanic black, or male. These data suggest that those who are aware of their kidney disease are more likely to achieve blood pressure control.
Authors:
Pantelis A Sarafidis; Suying Li; Shu-Cheng Chen; Allan J Collins; Wendy W Brown; Michael J Klag; George L Bakris
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of medicine     Volume:  121     ISSN:  1555-7162     ISO Abbreviation:  Am. J. Med.     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-03-31     Completed Date:  2008-04-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0267200     Medline TA:  Am J Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  332-40     Citation Subset:  AIM; IM    
Affiliation:
Hypertensive Diseases Unit, Section of Endocrinology, Diabetes, and Metabolism, University of Chicago-Pritzker School of Medicine, Chicago, IL 60637, USA.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Age Distribution
Aged
Antihypertensive Agents / therapeutic use*
Attitude to Health*
Awareness
Blood Pressure Determination
Chi-Square Distribution
Comorbidity
Cross-Sectional Studies
Female
Humans
Hypertension / diagnosis,  drug therapy*,  epidemiology*
Kidney Failure, Chronic / diagnosis,  epidemiology*,  therapy
Kidney Function Tests
Logistic Models
Male
Middle Aged
Odds Ratio
Patient Compliance
Predictive Value of Tests
Probability
Prognosis
Registries
Risk Assessment
Severity of Illness Index
Sex Distribution
Survival Analysis
Chemical
Reg. No./Substance:
0/Antihypertensive Agents

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