| Hypertension and atrial fibrillation. | |
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MedLine Citation:
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PMID: 19863867 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Atrial fibrillation (AF) is an emerging public health problem. The most important risk factor for developing chronic AF is uncontrolled hypertension. Uncontrolled hypertension promotes the initiation and perpetuation of AF through atrial remodeling. Experimental evidence has demonstrated the important role of the renin-angiotensin system in atrial remodeling. Retrospective analysis of several large clinical trials and small prospective trials suggests the beneficial role of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in preventing the onset and recurrence of AF in different populations. Several large prospective trials with longer follow-up periods are in progress. These trials may provide definitive evidence for the use of these agents in the prevention of AF. |
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Authors:
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Orson Go; Clive Rosendorff |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Current cardiology reports Volume: 11 ISSN: 1534-3170 ISO Abbreviation: Curr Cardiol Rep Publication Date: 2009 Nov |
Date Detail:
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Created Date: 2009-10-29 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100888969 Medline TA: Curr Cardiol Rep Country: United States |
Other Details:
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Languages: eng Pagination: 430-5 Citation Subset: IM |
Affiliation:
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Mount Sinai School of Medicine, Medicine (111), James J. Peters VA Medical Center, 130 West Kingsbridge Road, Bronx, NY 10468, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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