Document Detail

Hypertension as part of the metabolic syndrome.
MedLine Citation:
PMID:  18548089     Owner:  NLM     Status:  MEDLINE    
Obesity is known to be a major aetiological factor in the development of hypertension. It also leads to dyslipidaemia and raised blood glucose. All of these are components of the metabolic syndrome. Thus, hypertension, as part of the syndrome, is often found together with these other abnormalities. Obesity raises blood pressure by a number of mechanisms, including activation of the sympathetic nervous system and the renin- angiotensin system. Apart from cardiovascular disease and diabetes, the metabolic syndrome is also associated with fatty liver disease, sleep apnoea and some malignancies. Measures to reduce obesity through lifestyle changes are therefore highly desirable, not because of reductions in blood pressure alone.
Bmy Cheung
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Publication Detail:
Type:  Journal Article; Review     Date:  2008-06-12
Journal Detail:
Title:  Journal of human hypertension     Volume:  22     ISSN:  0950-9240     ISO Abbreviation:  J Hum Hypertens     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2008-11-21     Completed Date:  2009-01-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8811625     Medline TA:  J Hum Hypertens     Country:  England    
Other Details:
Languages:  eng     Pagination:  871-4     Citation Subset:  IM    
Department of Clinical Pharmacology, University of Birmingham, Birmingham, UK.
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MeSH Terms
Diabetes Mellitus, Type 2 / complications,  physiopathology
Hypertension / etiology*,  physiopathology*
Metabolic Syndrome X / complications*,  physiopathology*
Obesity / complications,  physiopathology

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