Document Detail

Hypertension and hydronephrosis: rapid resolution of high blood pressure following relief of bilateral ureteric obstruction.
MedLine Citation:
PMID:  22878855     Owner:  NLM     Status:  MEDLINE    
Hypertension secondary to hydronephrosis is not commonly reported in the medical literature. Tubuloglomerular feedback and the renin-angiotensin-aldosterone axis are thought to mediate this process. We describe a patient presenting with acute kidney injury and bilateral hydronephrosis secondary to pelvic malignancy in which peripheral venous renin and aldosterone were elevated. Her blood pressure improved rapidly following insertion of bilateral nephrostomies. The speed of resolution of hypertension following relief of obstruction suggests that humorally mediated vasoconstriction can play an important role in the mechanism by which hydronephrosis causes hypertension. We also discuss other causes of renal parenchymal compression that may lead to the development of hypertension.
Anil Chalisey; Mahzuz Karim
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2012-08-10
Journal Detail:
Title:  Journal of general internal medicine     Volume:  28     ISSN:  1525-1497     ISO Abbreviation:  J Gen Intern Med     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-02-25     Completed Date:  2013-08-22     Revised Date:  2014-03-09    
Medline Journal Info:
Nlm Unique ID:  8605834     Medline TA:  J Gen Intern Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  478-81     Citation Subset:  IM    
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MeSH Terms
Acute Kidney Injury / complications
Hydronephrosis / complications*,  diagnosis,  surgery
Hypertension / etiology*
Magnetic Resonance Imaging
Nephrostomy, Percutaneous
Pelvic Neoplasms / complications,  secondary
Ureteral Obstruction / complications*,  surgery

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