Document Detail

Hypersensitivity to non-steroidal anti-inflammatory drugs--asthma precipitated by zomepirac. A case report.
MedLine Citation:
PMID:  6695277     Owner:  NLM     Status:  MEDLINE    
Non-steroidal anti-inflammatory agents can precipitate an asthma attack of varying severity. The most likely mechanism is the inhibition of the production of prostaglandin E with a concomitant increase in the production of the leukotrienes. A case in which an attack of asthma was precipitated by ingestion of 50 mg zomepirac (Zomax) and the patient responded to inhaled fenoterol is described. We conclude that zomepirac can cause reversible airflow limitation.
J J Botha; D J Weich
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde     Volume:  65     ISSN:  0256-9574     ISO Abbreviation:  S. Afr. Med. J.     Publication Date:  1984 Feb 
Date Detail:
Created Date:  1984-03-08     Completed Date:  1984-03-08     Revised Date:  2014-09-12    
Medline Journal Info:
Nlm Unique ID:  0404520     Medline TA:  S Afr Med J     Country:  SOUTH AFRICA    
Other Details:
Languages:  eng     Pagination:  180-2     Citation Subset:  IM    
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MeSH Terms
Analgesics / adverse effects*
Aspirin / adverse effects
Asthma / chemically induced*
Middle Aged
Pyrroles / adverse effects*
Time Factors
Tolmetin / adverse effects*,  analogs & derivatives
Reg. No./Substance:
0/Analgesics; 0/Pyrroles; 822G987U9J/zomepirac; D8K2JPN18B/Tolmetin; R16CO5Y76E/Aspirin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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