Document Detail

Hypersensitivity pneumonitis due to molds in a saxophone player.
MedLine Citation:
PMID:  20822994     Owner:  NLM     Status:  MEDLINE    
This 48-year-old patient was evaluated for an interstitial pneumonia. An open-lung biopsy showed a pattern of nonspecific interstitial pneumonia. The CT scan appearance, showing mosaic ground-glass opacities in the ventilated parts of the lung, the centrolobular predominance of inflammation on the lung sections, and the presence of a lymphocytic alveolitis at BAL suggested a hypersensitivity pneumonitis. The patient was a white-collar worker and had no contact with pets, birds, drugs, or molds at home. He used to play the saxophone as a hobby. Two molds, Ulocladium botrytis and Phoma sp, were detected in the saxophone. Precipitating antibodies to these molds were present in his serum. An additional study confirmed the frequent colonization of saxophones with potentially pathogenic molds, such as Fusarium sp, Penicillium sp, and Cladosporium sp. Respiratory physicians should be aware of the risk of hypersensitivity pneumonitis in saxophone or perhaps other wind instrument players.
Flora Metzger; Amaryllis Haccuria; Gabriel Reboux; Nicole Nolard; Jean-Charles Dalphin; Paul De Vuyst
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Chest     Volume:  138     ISSN:  1931-3543     ISO Abbreviation:  Chest     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-09-08     Completed Date:  2010-10-14     Revised Date:  2011-04-07    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  United States    
Other Details:
Languages:  eng     Pagination:  724-6     Citation Subset:  AIM; IM    
Department of Respiratory Disease, Jean Minjoz University Hospital, Besançon, France.
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MeSH Terms
Alveolitis, Extrinsic Allergic / diagnosis*,  microbiology*,  therapy
Lung Diseases, Interstitial / diagnosis,  microbiology*,  therapy
Middle Aged
Occupational Diseases / diagnosis,  microbiology*,  therapy
Comment In:
Chest. 2011 Mar;139(3):729; author reply 729-30   [PMID:  21362668 ]
Chest. 2010 Sep;138(3):467-8   [PMID:  20822980 ]

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