| Hypersensitivity myocarditis complicating hypertrophic cardiomyopathy heart. | |
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MedLine Citation:
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PMID: 15266362 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The present report describes a case of eosinophilic myocarditis complicating hypertrophic cardiomyopathy. The 47-year-old female patient, known to have hypertrophic cardiomyopathy, was admitted with biventricular failure and managed aggressively with dobutamine infusion and other drugs while being assessed for heart transplantation. On transthoracic echocardiogram, she had moderate left ventricular dysfunction with regional variability and moderate mitral regurgitation. The recipient's heart showed the features of apical hypertrophic cardiomyopathy and myocarditis with abundant eosinophils. Myocarditis is rare and eosinophilic myocarditis is rarer. It is likely that the hypersensitivity (eosinophilic) myocarditis was related to dobutamine infusion therapy. Eosinophilic myocarditis has been reported with an incidence of 2.4% to 7.2% in explanted hearts and may be related to multidrug therapy. |
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Authors:
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Jagdish Butany; Vidhya Nair; Manmeet S Ahluwalia; James Graba; Dina El Demellawy; Vivek Rao; Heather Ross |
Publication Detail:
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Type: Case Reports; Editorial |
Journal Detail:
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Title: The Canadian journal of cardiology Volume: 20 ISSN: 0828-282X ISO Abbreviation: Can J Cardiol Publication Date: 2004 Jul |
Date Detail:
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Created Date: 2004-07-21 Completed Date: 2004-09-17 Revised Date: 2008-04-09 |
Medline Journal Info:
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Nlm Unique ID: 8510280 Medline TA: Can J Cardiol Country: Canada |
Other Details:
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Languages: eng Pagination: 911-4 Citation Subset: IM |
Affiliation:
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Department of Pathology, Toronto General Hospital, Toronto, Ontario. jagdish.butany@uhn.on.ca |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenergic beta-Agonists
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adverse effects Cardiomyopathy, Hypertrophic / drug therapy*, physiopathology, ultrasonography Dobutamine / adverse effects Drug Hypersensitivity* Echocardiography Female Heart Failure / drug therapy, physiopathology, ultrasonography Humans Middle Aged Mitral Valve Insufficiency / drug therapy, physiopathology, ultrasonography Myocarditis / chemically induced*, physiopathology, ultrasonography Myocardium / pathology Stroke Volume / physiology Ventricular Dysfunction, Left / drug therapy, physiopathology, ultrasonography |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic beta-Agonists; 34368-04-2/Dobutamine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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