Document Detail

Hypersensitivity from Intravenous Iron Products.
MedLine Citation:
PMID:  25017687     Owner:  NLM     Status:  Publisher    
In the last several years, intravenous therapy with iron products has been more widely used. Although it has been a standard procedure in dialysis-associated anemia since the early 1990s, its use is expanding to a host of conditions associated with iron deficiency, especially young women with heavy uterine bleeding and pregnancy. Free iron is associated with unacceptable high toxicity inducing severe, hemodynamically significant symptoms. Subsequently, formulations that contain the iron as an iron carbohydrate nanoparticle have been designed. With newer formulations, including low-molecular-weight iron dextran, iron sucrose, ferric gluconate, ferumoxytol, iron isomaltoside, and ferric carboxymaltose, serious adverse events are rare.
Andreas J Bircher; Michael Auerbach
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Publication Detail:
Type:  REVIEW    
Journal Detail:
Title:  Immunology and allergy clinics of North America     Volume:  34     ISSN:  1557-8607     ISO Abbreviation:  Immunol Allergy Clin North Am     Publication Date:  2014 Aug 
Date Detail:
Created Date:  2014-7-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8805635     Medline TA:  Immunol Allergy Clin North Am     Country:  -    
Other Details:
Languages:  ENG     Pagination:  707-723     Citation Subset:  -    
Copyright Information:
Copyright © 2014 Elsevier Inc. All rights reserved.
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