Document Detail


Hypersensitivity of delayed type in hypertensive patients.
MedLine Citation:
PMID:  1993116     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The agarose migration technique was used for demonstration of delayed-type hypersensitivity to arterial vessel wall antigens in patients suffering from chronic essential hypertension. By means of this technique, it was demonstrated that the migration indices from the hypertensive patients differed significantly from the normotensive control persons, P less than 0.005. The significant difference was abolished when anti-LIF was added to the migration tests. This means that a hypersensitivity of the delayed type had developed in the hypertensive patients and the results indicated that the hypersensitivity was an autoimmunity to arterial vessel wall antigens.
Authors:
F Olsen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  APMIS : acta pathologica, microbiologica, et immunologica Scandinavica     Volume:  99     ISSN:  0903-4641     ISO Abbreviation:  APMIS     Publication Date:  1991 Jan 
Date Detail:
Created Date:  1991-03-15     Completed Date:  1991-03-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8803400     Medline TA:  APMIS     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  65-8     Citation Subset:  IM    
Affiliation:
Institute of Hygiene, University of Copenhagen, Denmark.
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MeSH Terms
Descriptor/Qualifier:
Adult
Animals
Cell Migration Inhibition
Female
Humans
Hypersensitivity, Delayed*
Hypertension / immunology*
Leukocyte Migration-Inhibitory Factors / immunology
Male
Middle Aged
Rabbits
Chemical
Reg. No./Substance:
0/Leukocyte Migration-Inhibitory Factors

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