Document Detail

Hyperreninemia during renal transplantation.
MedLine Citation:
PMID:  370629     Owner:  NLM     Status:  MEDLINE    
18 patients undergoing renal transplantation were studied prospectively to determine the incidence and mechanism of blood pressure elevations which sometimes occur after release of vascular clamps from the grafts. No patients became as severely hypertensive as noted in previous reports. A weak, but statistically significant (r=0.56, p less than 0.05) positive correlation was found between changes in plasma renin activity and small incremental changes in blood pressure. 2 patients in whom the greatest change in renin occurred showed little or no increase in blood pressure. In view of the small blood pressure changes seen in the face of significant changes in plasma renin activity, it appears unlikely that acute hyperreninemia alone is sufficient explanation for postdeclamping hypertension which is sometimes observed during renal transplantation.
R D Levine; M D Blaufox
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Nephron     Volume:  22     ISSN:  0028-2766     ISO Abbreviation:  Nephron     Publication Date:  1978  
Date Detail:
Created Date:  1979-05-24     Completed Date:  1979-05-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0331777     Medline TA:  Nephron     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  226-31     Citation Subset:  IM    
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MeSH Terms
Hypertension / etiology
Kidney Transplantation*
Prospective Studies
Renin / blood*
Transplantation, Homologous / adverse effects
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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