| Hyperreactio luteinalis with both markedly elevated human chorionic gonadotropin levels and an imbalance of angiogenic factors subsequently developed severe early-onset preeclampsia. | |
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MedLine Citation:
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PMID: 19446290 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To report a case of hyperreactio luteinalis (HL) with elevated levels of human chorionic gonadotropin (hCG) and a severe imbalance of angiogenic factors, which developed into severe, early onset preeclampsia (PE). DESIGN: Case report. SETTING: University perinatal center. PATIENT(S): A 32-year-old primigravida woman with HL, high hCG levels, and severe imbalance of angiogenic factors who subsequently developed severe PE. INTERVENTION(S): Emergent cesarean section due to nonreassuring fetal status. MAIN OUTCOME MEASURE(S): Severe, early onset PE. RESULT(S): A case of HL was referred to our hospital for remarkably elevated hCG levels and bilaterally enlarged multicystic ovaries in the first trimester; the patient subsequently developed severe, early onset PE with a severe imbalance of angiogenic factors. Emergency cesarean section was performed, and she delivered a premature female infant weighing 1818 g at 32 week's gestational age. During her next pregnancy, the circulating levels of hCG and angiogenic factors remained normal, and she did not develop either PE or HL. CONCLUSION(S): Although HL complicated with PE is very rare, our case suggests that HL associated with both an elevated hCG level and an imbalance of angiogenic factors might be a risk/predictive factor for severe, early onset PE. |
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Authors:
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Hisashi Masuyama; Yoko Tateishi; Miwa Matsuda; Yuji Hiramatrsu |
Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't Date: 2009-05-14 |
Journal Detail:
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Title: Fertility and sterility Volume: 92 ISSN: 1556-5653 ISO Abbreviation: Fertil. Steril. Publication Date: 2009 Jul |
Date Detail:
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Created Date: 2009-06-29 Completed Date: 2009-07-29 Revised Date: 2009-11-25 |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: United States |
Other Details:
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Languages: eng Pagination: 393.e1-3 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University, Okayama, Japan. masuyama@cc.okayama-u.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cesarean Section Chorionic Gonadotropin / blood* Female Humans Infant, Newborn Magnetic Resonance Imaging Ovarian Cysts / complications*, pathology Ovarian Neoplasms / pathology*, ultrasonography Pre-Eclampsia / etiology, surgery*, ultrasonography Pregnancy Pregnancy Complications / pathology Pregnancy Proteins / blood |
| Chemical | |
Reg. No./Substance:
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0/Chorionic Gonadotropin; 0/Pregnancy Proteins; 144589-93-5/placenta growth factor |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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