Document Detail

Hyperoxia during recovery from consecutive anaerobic exercises in the sickle cell trait.
MedLine Citation:
PMID:  7588697     Owner:  NLM     Status:  MEDLINE    
The sickle cell trait (HbAS) does not affect anaerobic exercise performance. However, lower blood lactate concentrations ([La-]) are consistently found during repeated anaerobic exercise in HbAS, and could be related to type of recovery. To study this, on three different occasions 17 HbAS and 17 matched control athletes (HbAA) underwent a series of three maximal cycle exercise tests of approximately 2-min duration, separated by 10-min recovery periods of rest, breathing either room air (P) or 100% oxygen (H), or of light pedaling (A). In all tests, work performed, heart rate, blood hematocrit, and [La-] were measured. Despite similar evolution of performance in each series of three anaerobic exercises, significantly lower [La-] were consistently found in HbAS in P and A, compared to HbAA (P < 0.0001). However, in H, similar [La-] was found in HbAS and HbAA. Higher mean heart rates were consistently measured in HbAS at exhaustion, and during the first 4 min of recovery, these differences being unrelated to type of recovery. We conclude that type of recovery does not influence subsequent performance in HbAS or HbAA. We speculate that improved regional oxygen availability in exercising muscle is associated with marked modification of lactate kinetics in highly trained HbAS, but not in similarly fit HbAA athletes.
P Thiriet; D Wouassi; E Bitanga; J R Lacour; D Gozal
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European journal of applied physiology and occupational physiology     Volume:  71     ISSN:  0301-5548     ISO Abbreviation:  Eur J Appl Physiol Occup Physiol     Publication Date:  1995  
Date Detail:
Created Date:  1995-12-13     Completed Date:  1995-12-13     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0410266     Medline TA:  Eur J Appl Physiol Occup Physiol     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  253-8     Citation Subset:  IM; S    
UFR-APS, University of Lyon 1, CRIS, France.
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MeSH Terms
Exercise Test
Heart Rate
Hyperoxia / physiopathology*
Lactates / blood
Lactic Acid
Osmolar Concentration
Physical Exertion*
Reference Values
Sickle Cell Trait / physiopathology*
Reg. No./Substance:
0/Lactates; 50-21-5/Lactic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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