Document Detail

Hyperosmolar hyperglycemic nonketotic coma. A complication of short-term systemic corticosteroid use.
MedLine Citation:
PMID:  6657199     Owner:  NLM     Status:  MEDLINE    
Hyperosmolar hyperglycemic nonketotic coma is a serious and often lethal clinical biochemical syndrome. We report three cases of ophthalmic problems that were treated with a short course of oral corticosteroids and which resulted in the development of hyperosmolar hyperglycemic nonketotic coma. Two of these cases concerned relatively young, previously healthy patients and had fatal outcomes. The third patient, who was elderly, survived because of early detection and initiation of therapy. All three cases demonstrate that hyperosmolar hyperglycemic nonketotic coma is a serious potential complication of systemic steroidal therapy, even in a short course of treatment such as is often used in ophthalmology.
L S Fujikawa; D M Meisler; R A Nozik
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Ophthalmology     Volume:  90     ISSN:  0161-6420     ISO Abbreviation:  Ophthalmology     Publication Date:  1983 Oct 
Date Detail:
Created Date:  1984-02-14     Completed Date:  1984-02-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7802443     Medline TA:  Ophthalmology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1239-42     Citation Subset:  IM    
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MeSH Terms
Administration, Oral
Adrenal Cortex Hormones / administration & dosage,  adverse effects*
Diabetes Complications
Diabetic Coma / chemically induced*
Eye Diseases / drug therapy
Hyperglycemic Hyperosmolar Nonketotic Coma / chemically induced*,  mortality,  physiopathology
Obesity / complications
Reg. No./Substance:
0/Adrenal Cortex Hormones

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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