| Hyperkinetic borderline hypertension in Tecumseh, Michigan. | |
| | |
MedLine Citation:
|
PMID: 1848264 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Of 691 healthy (untreated) villagers of Tecumseh, Michigan (average age 32.6 years), 99 had a clinical blood pressure exceeding 140/90 mmHg. Thirty-seven per cent of these borderline hypertensives had increased heart rate, cardiac index, forearm blood flow and plasma norepinephrine. These subjects had elevated self-determined home blood pressure (average of 14 measurements). The present hyperkinetic borderlines had elevated blood pressure at 5, 8, 21 and 23 years of age and their parents also had higher blood pressure. The prevalence of high blood pressure in Tecumseh, its long history, elevated blood pressure readings outside the physician's office and family background of hypertension, suggests that the hyperkinetic state is a significant clinical condition. Previous studies on hospital-based populations proved that the hyperkinetic state is caused by an excessive autonomic drive. The association of the hyperkinetic state with elevated norepinephrine in this study suggests that a sympathetic hyperactivity is present in a large proportion of unselected subjects with mild blood pressure elevation. |
| | |
Authors:
|
S Julius; L Krause; N J Schork; A D Mejia; K A Jones; C van de Ven; E H Johnson; M A Sekkarie; S E Kjeldsen; J Petrin |
Related Documents
:
|
8979524 - Brainstem auditory evoked responses in primary hypertension. 6705484 - Studies of salivary flow in borderline hypertension: effects of drugs acting on structu... 7180584 - Blood pressure, cardiac output and systemic vascular resistance during rest, muscle wor... 3192294 - Arterial hypertension is associated with hypalgesia in humans. 16696364 - Management of a tracheal tear during laryngopharyngoesophagectomy with gastric pull-up. 15198884 - Effect of continuous positive airway pressure treatment on vascular endothelial functio... |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
|
Title: Journal of hypertension Volume: 9 ISSN: 0263-6352 ISO Abbreviation: J. Hypertens. Publication Date: 1991 Jan |
Date Detail:
|
Created Date: 1991-04-15 Completed Date: 1991-04-15 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8306882 Medline TA: J Hypertens Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 77-84 Citation Subset: IM |
Affiliation:
|
University of Michigan Medical Center, Division of Hypertension, Ann Arbor 48109-0356. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Echocardiography, Doppler Female Hemodynamics / physiology* Humans Hyperkinesis* Hypertension / epidemiology* Longitudinal Studies Male Michigan / epidemiology Norepinephrine / blood Population Surveillance Prevalence Risk Factors Sympathetic Nervous System / physiopathology* |
| Grant Support | |
ID/Acronym/Agency:
|
HL37464/HL/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
|
51-41-2/Norepinephrine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Chronic intracerebroventricular infusions of endothelin elevate arterial pressure in rats.
Next Document: Fetal liver cell transplantation fails to transfer hypertension from genetically hypertensive rats t...