Document Detail


Hyperkalemic cardiac arrest after cardiopulmonary bypass in a child with unsuspected duchenne muscular dystrophy.
MedLine Citation:
PMID:  15728050     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Adverse reactions to volatile anesthetics and depolarizing muscle relaxants can occur in patients with Duchenne muscular dystrophy (DMD) resulting in acute rhabdomyolysis and hyperkalemia. We report a case of hyperkalemic cardiac arrest after cardiac surgery using cardiopulmonary bypass in a child with unsuspected DMD. Early diagnosis and management of hyperkalemia resulted in a successful outcome. Genetic testing confirmed the diagnosis of DMD. We recommend a thorough preoperative investigation, including creatine kinase estimation, in children with a history of unexplained motor delay.
Authors:
Aruna Nathan; Arjunan Ganesh; Rodolfo I Godinez; Susan C Nicolson; William J Greeley
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Anesthesia and analgesia     Volume:  100     ISSN:  0003-2999     ISO Abbreviation:  Anesth. Analg.     Publication Date:  2005 Mar 
Date Detail:
Created Date:  2005-02-24     Completed Date:  2005-03-18     Revised Date:  2005-11-22    
Medline Journal Info:
Nlm Unique ID:  1310650     Medline TA:  Anesth Analg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  672-4, table of contents     Citation Subset:  AIM; IM    
Affiliation:
Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, PA 19104-4399, USA.
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MeSH Terms
Descriptor/Qualifier:
Cardiopulmonary Bypass / adverse effects*
Child, Preschool
Creatine Kinase / blood
Heart Arrest / etiology*
Humans
Hyperkalemia / etiology*
Male
Muscular Dystrophy, Duchenne / complications*
Chemical
Reg. No./Substance:
EC 2.7.3.2/Creatine Kinase
Comments/Corrections
Comment In:
Anesth Analg. 2005 Nov;101(5):1561-2; author reply 1562   [PMID:  16244038 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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