Document Detail


Hyperkalemia and cocaine induced dynamic Brugada-type electrocardiogram.
MedLine Citation:
PMID:  19641464     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Brugada syndrome is a well-defined clinical entity with the typical electrocardiographic changes in the right precordial leads (V1 and V2), attributed to mutation in SCN5A gene. Brugada-like electrocardiographic pattern can be replicated by sodium channel-blocking drugs and electrolyte abnormalities. We describe a 46-year-old individual, who presented with hyperkalemia secondary to muscle damage and renal insufficiency, after abusing cocaine. The electrocardiogram showed Brugada sign. The electrocardiogram changes disappeared after sodium bicarbonate administration and normalization of serum potassium. The case highlights the importance of recognizing cocaine and hyperkalemia, as potential triggers of the acquired Brugada sign.
Authors:
Farzan Irani; Rahil Kasmani; Yousuf Kanjwal
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of emergency medicine : official journal of the European Society for Emergency Medicine     Volume:  17     ISSN:  1473-5695     ISO Abbreviation:  Eur J Emerg Med     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-10-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9442482     Medline TA:  Eur J Emerg Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  113-5     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, St. Vincent Mercy Medical Center, University of Toledo Medical Center, Toledo, Ohio 43608, USA. farzan_i@yahoo.com
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