Document Detail


Hyperkalaemia, cardiac arrhythmias, and cerebral lesions in high risk neonates.
MedLine Citation:
PMID:  3688918     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The case notes of 20 infants with hyperkalaemia (defined as two successive serum potassium measurements of greater than 7.5 mmol/l) were reviewed. The incidence of hyperkalaemia was also looked at in an unselected population of 200 low birthweight infants. The mean gestational age of the 20 affected infants was 29 weeks and the mean birth weight 1235 g. The incidence of hyperkalemia in the cohort of 200 infants weighing less than 1500 g at birth was 3.5%. Hyperkalaemia was associated with a high incidence of cardiac arrhythmia (60%), impaired renal function (50%), and changes on cerebral ultrasonography (88%). Hyperkalaemia responds slowly to conventional treatment with dextrose, insulin, and exchange resins. There is a close temporal relation in some infants between hyperkalaemia and cardiac arrhythmias and periventricular leukomalacia, suggesting a causal association.
Authors:
D Shortland; J Q Trounce; M I Levene
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of disease in childhood     Volume:  62     ISSN:  1468-2044     ISO Abbreviation:  Arch. Dis. Child.     Publication Date:  1987 Nov 
Date Detail:
Created Date:  1987-12-31     Completed Date:  1987-12-31     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372434     Medline TA:  Arch Dis Child     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1139-43     Citation Subset:  AIM; IM    
Affiliation:
Department of Child Health, Leicester Royal Infirmary.
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MeSH Terms
Descriptor/Qualifier:
Arrhythmias, Cardiac / etiology*
Bradycardia / etiology
Cerebral Hemorrhage / etiology*
Encephalomalacia / etiology*
Humans
Hyperkalemia / complications*
Infant, Low Birth Weight
Infant, Newborn
Leukomalacia, Periventricular / etiology*
Risk Factors
Tachycardia, Supraventricular / etiology
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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